FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term regulation of protein catabolic process ID (Ontology) GO:0042176 (Gene Ontology)
Definition Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
Also Known As "regulation of cellular protein breakdown" ; "regulation of cellular protein catabolic process" ; "regulation of cellular protein catabolism" (for all, see Synonyms field below)
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       5
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 regulation of protein catabolic process (all annotations which use CV term, excluding "NOT" statements)       5
     involved_in | regulation of protein catabolic process       5
Spanning Tree (Parents/Children)
Only view relationship: 
regulation of metabolic process
 |__regulation of catabolic process____________
regulation of macromolecule metabolic process  |
 |__regulation of protein metabolic process____|
regulation of primary metabolic process        |
 |__regulation of protein metabolic process____|
                                               regulation of protein catabolic process  91 rec.
                                                |__negative regulation of protein catabolic process 18 rec.
                                                |   |__negative regulation of chaperone-mediated autophagy
                                                |   |__negative regulation of elastin catabolic process
                                                |   |__negative regulation of low-density lipoprotein particle receptor catabolic process
                                                |   |__negative regulation of membrane protein ectodomain proteolysis 1 rec.
                                                |   |__negative regulation of proteasomal protein catabolic process(+) 15 rec.
                                                |   |__negative regulation of protein catabolic process in the vacuole(+) 1 rec.
                                                |   |__negative regulation of proteolysis associated with antigen processing and presentation
                                                |__positive regulation of protein catabolic process 68 rec.
                                                |   |__positive regulation of chaperone-mediated autophagy
                                                |   |__positive regulation of elastin catabolic process
                                                |   |__positive regulation of low-density lipoprotein particle receptor catabolic process
                                                |   |__positive regulation of membrane protein ectodomain proteolysis
                                                |   |__positive regulation of proteasomal protein catabolic process(+) 52 rec.
                                                |   |__positive regulation of protein catabolic process in the vacuole(+) 1 rec.
                                                |   |__positive regulation of proteolysis associated with antigen processing and presentation
                                                |__regulation of chaperone-mediated autophagy
                                                |   |__negative regulation of chaperone-mediated autophagy
                                                |   |__positive regulation of chaperone-mediated autophagy
                                                |__regulation of elastin catabolic process
                                                |   |__negative regulation of elastin catabolic process
                                                |   |__positive regulation of elastin catabolic process
                                                |__regulation of low-density lipoprotein particle receptor catabolic process
                                                |   |__negative regulation of low-density lipoprotein particle receptor catabolic process
                                                |   |__positive regulation of low-density lipoprotein particle receptor catabolic process
                                                |__regulation of membrane protein ectodomain proteolysis 1 rec.
                                                |   |__negative regulation of membrane protein ectodomain proteolysis 1 rec.
                                                |   |__positive regulation of membrane protein ectodomain proteolysis
                                                |__regulation of proteasomal protein catabolic process 68 rec.
                                                |   |__negative regulation of proteasomal protein catabolic process(+) 15 rec.
                                                |   |__positive regulation of proteasomal protein catabolic process(+) 52 rec.
                                                |   |__regulation of ERAD pathway(+) 4 rec.
                                                |   |__regulation of proteasomal ubiquitin-dependent protein catabolic process(+) 58 rec.
                                                |__regulation of protein catabolic process at postsynapse, modulating synaptic transmission
                                                |__regulation of protein catabolic process at presynapse, modulating synaptic transmission
                                                |__regulation of protein catabolic process in the vacuole 2 rec.
                                                |   |__negative regulation of protein catabolic process in the vacuole(+) 1 rec.
                                                |   |__positive regulation of protein catabolic process in the vacuole(+) 1 rec.
                                                |   |__regulation of lysosomal protein catabolic process(+) 2 rec.
                                                |__regulation of PSII associated light-harvesting complex II catabolic process
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Is a regulation of catabolic process
regulation of protein metabolic process
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Synonyms
  • "regulation of cellular protein breakdown" EXACT
    "regulation of cellular protein catabolic process" EXACT
    "regulation of cellular protein catabolism" EXACT
    "regulation of cellular protein degradation" EXACT
    "regulation of cyclin breakdown" NARROW
    "regulation of cyclin catabolic process" NARROW
    "regulation of cyclin catabolism" NARROW
    "regulation of cyclin degradation" NARROW
    "regulation of degradation of cyclin" NARROW
    "regulation of protein breakdown" EXACT
    "regulation of protein catabolism" EXACT
    "regulation of protein degradation" EXACT
Secondary IDs
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