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General Information
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| Term |
error-prone translesion synthesis |
ID (Ontology) |
GO:0042276 (Gene Ontology) |
| Definition |
The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites.[ PubMed:11485998 ] |
| Also Known As |
"mutagenic PRR" |
| Comment |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_BIOLOGICAL_PROCESS | 3 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Genes |
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error-prone translesion synthesis (all annotations which use CV term, excluding "NOT" statements) | 3 | involved_in | error-prone translesion synthesis | 3 | NOT | involved_in | error-prone translesion synthesis | 1 |
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Relationships
