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| Term | MHC class I peptide loading complex | ID (Ontology) | GO:0042824 (Gene Ontology) |
| Definition | A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules.[ PubMed:10631934 ] | ||
| Also Known As | "peptide-loading complex" | ||
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endoplasmic reticulum |__endoplasmic reticulum protein-containing complex___________ membrane | |__membrane protein complex___________________________________| organelle membrane | |__endoplasmic reticulum membrane_____________________________| protein-containing complex | |__membrane protein complex___________________________________| |__endoplasmic reticulum protein-containing complex___________| nuclear outer membrane-endoplasmic reticulum membrane network | |__endoplasmic reticulum membrane_____________________________| endoplasmic reticulum subcompartment | |__endoplasmic reticulum membrane_____________________________| MHC class I peptide loading complex |__TAP complex |__Tapasin-ERp57 complex |
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| Is a |
membrane protein complex endoplasmic reticulum protein-containing complex |
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| Part of | endoplasmic reticulum membrane | ||
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