FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term activation of Janus kinase activity ID (Ontology) GO:0042976 (Gene Ontology)
Definition The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.[ PubMed:12479803 ]
Also Known As "activation of JAK protein" ; "activation of JAK protein by tyrosine phosphorylation" ; "positive regulation of JAK protein activity by tyrosine phosphorylation" (for all, see Synonyms field below)
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protein phosphorylation
 |__peptidyl-tyrosine phosphorylation_______________________________
peptidyl-tyrosine modification                                      |
 |__peptidyl-tyrosine phosphorylation_______________________________|
positive regulation of protein kinase activity                      |
 |__activation of protein kinase activity___________________________|
regulation of receptor signaling pathway via JAK-STAT               |
 |__positive regulation of receptor signaling pathway via JAK-STAT__|
positive regulation of receptor signaling pathway via STAT          |
 |__positive regulation of receptor signaling pathway via JAK-STAT__|
                                                                    activation of Janus kinase activity
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Is a peptidyl-tyrosine phosphorylation
activation of protein kinase activity
Part of positive regulation of receptor signaling pathway via JAK-STAT
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Synonyms
  • "activation of JAK protein" EXACT
    "activation of JAK protein by tyrosine phosphorylation" EXACT
    "activation of JAK1 kinase activity" NARROW
    "activation of JAK1 protein" NARROW
    "activation of JAK2 kinase activity" NARROW
    "activation of JAK2 protein" NARROW
    "positive regulation of JAK protein activity by tyrosine phosphorylation" EXACT
    "tyrosine phosphorylation of JAK protein" EXACT
    "tyrosine phosphorylation of JAK1 protein" NARROW
    "tyrosine phosphorylation of JAK2 protein" NARROW
Secondary IDs
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