FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term regulation of apoptotic process ID (Ontology) GO:0042981 (Gene Ontology)
Definition Any process that modulates the occurrence or rate of cell death by apoptotic process.
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      32
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 regulation of apoptotic process (all annotations which use CV term, excluding "NOT" statements)       1     32
     involved_in | regulation of apoptotic process       --      32
Spanning Tree (Parents/Children)
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  regulation of cellular process
   |__regulation of programmed cell death
       |__regulation of apoptotic process  218 rec.
           |__negative regulation of apoptotic process 126 rec.
           |   |__negative regulation of anoikis
           |   |__negative regulation of apoptotic process in bone marrow cell
           |   |__negative regulation of apoptotic process involved in development(+) 2 rec.
           |   |__negative regulation of apoptotic signaling pathway(+) 22 rec.
           |   |__negative regulation of compound eye retinal cell apoptotic process 1 rec.
           |   |__negative regulation of endothelial cell apoptotic process
           |   |__negative regulation of epithelial cell apoptotic process(+)
           |   |__negative regulation of execution phase of apoptosis(+) 1 rec.
           |   |__negative regulation of fat cell apoptotic process
           |   |__negative regulation of fibroblast apoptotic process
           |   |__negative regulation of glial cell apoptotic process(+) 1 rec.
           |   |__negative regulation of leukocyte apoptotic process(+)
           |   |__negative regulation of mesenchymal cell apoptotic process(+)
           |   |__negative regulation of muscle cell apoptotic process(+)
           |   |__negative regulation of myeloid cell apoptotic process(+)
           |   |__negative regulation of myofibroblast cell apoptotic process
           |   |__negative regulation of neuron apoptotic process(+) 22 rec.
           |__positive regulation of apoptotic process 67 rec.
           |   |__positive regulation of anoikis
           |   |__positive regulation of apoptotic process in bone marrow cell
           |   |__positive regulation of apoptotic process involved in development(+) 9 rec.
           |   |__positive regulation of apoptotic signaling pathway(+) 6 rec.
           |   |__positive regulation of compound eye retinal cell apoptotic process 1 rec.
           |   |__positive regulation of endothelial cell apoptotic process
           |   |__positive regulation of epithelial cell apoptotic process(+)
           |   |__positive regulation of execution phase of apoptosis
           |   |__positive regulation of fat cell apoptotic process
           |   |__positive regulation of fibroblast apoptotic process
           |   |__positive regulation of glial cell apoptotic process(+) 1 rec.
           |   |__positive regulation of leukocyte apoptotic process(+)
           |   |__positive regulation of mesenchymal cell apoptotic process(+)
           |   |__positive regulation of muscle cell apoptotic process(+)
           |   |__positive regulation of myeloid cell apoptotic process(+)
           |   |__positive regulation of myofibroblast cell apoptotic process
           |   |__positive regulation of neuron apoptotic process(+) 10 rec.
           |__regulation of anoikis
           |   |__negative regulation of anoikis
           |   |__positive regulation of anoikis
           |__regulation of apoptosis involved in tissue homeostasis 1 rec.
           |__regulation of apoptotic process in bone marrow cell
           |   |__negative regulation of apoptotic process in bone marrow cell
           |   |__positive regulation of apoptotic process in bone marrow cell
           |__regulation of apoptotic process involved in development 14 rec.
           |   |__negative regulation of apoptotic process involved in development(+) 2 rec.
           |   |__positive regulation of apoptotic process involved in development(+) 9 rec.
           |   |__regulation of apoptotic process involved in metanephric collecting duct development(+)
           |   |__regulation of apoptotic process involved in metanephric nephron tubule development(+)
           |   |__regulation of apoptotic process involved in morphogenesis(+) 2 rec.
           |   |__regulation of B cell deletion(+)
           |   |__regulation of mesenchymal cell apoptotic process involved in metanephros development(+)
           |   |__regulation of nurse cell apoptotic process(+) 10 rec.
           |__regulation of apoptotic signaling pathway 30 rec.
           |   |__negative regulation of apoptotic signaling pathway(+) 22 rec.
           |   |__positive regulation of apoptotic signaling pathway(+) 6 rec.
           |   |__regulation of extrinsic apoptotic signaling pathway(+) 4 rec.
           |   |__regulation of intrinsic apoptotic signaling pathway(+) 9 rec.
           |__regulation of compound eye retinal cell apoptotic process 2 rec.
           |   |__negative regulation of compound eye retinal cell apoptotic process 1 rec.
           |   |__positive regulation of compound eye retinal cell apoptotic process 1 rec.
           |__regulation of endothelial cell apoptotic process
           |   |__negative regulation of endothelial cell apoptotic process
           |   |__positive regulation of endothelial cell apoptotic process
           |__regulation of epithelial cell apoptotic process
           |   |__negative regulation of epithelial cell apoptotic process(+)
           |   |__positive regulation of epithelial cell apoptotic process(+)
           |   |__regulation of cholangiocyte apoptotic process(+)
           |   |__regulation of granulosa cell apoptotic process(+)
           |   |__regulation of hepatocyte apoptotic process(+)
           |   |__regulation of keratinocyte apoptotic process(+)
           |   |__regulation of podocyte apoptotic process(+)
           |   |__regulation of type B pancreatic cell apoptotic process(+)
           |__regulation of fat cell apoptotic process
           |   |__negative regulation of fat cell apoptotic process
           |   |__positive regulation of fat cell apoptotic process
           |__regulation of fibroblast apoptotic process
           |   |__negative regulation of fibroblast apoptotic process
           |   |__positive regulation of fibroblast apoptotic process
           |__regulation of glial cell apoptotic process 2 rec.
           |   |__negative regulation of glial cell apoptotic process(+) 1 rec.
           |   |__positive regulation of glial cell apoptotic process(+) 1 rec.
           |   |__regulation of oligodendrocyte apoptotic process(+)
           |__regulation of leukocyte apoptotic process
           |   |__negative regulation of leukocyte apoptotic process(+)
           |   |__positive regulation of leukocyte apoptotic process(+)
           |   |__regulation of dendritic cell apoptotic process(+)
           |   |__regulation of lymphocyte apoptotic process(+)
           |   |__regulation of macrophage apoptotic process(+)
           |   |__regulation of mast cell apoptotic process(+)
           |   |__regulation of neutrophil apoptotic process(+)
           |__regulation of mesenchymal cell apoptotic process
           |   |__negative regulation of mesenchymal cell apoptotic process(+)
           |   |__positive regulation of mesenchymal cell apoptotic process(+)
           |   |__regulation of mesenchymal cell apoptotic process involved in metanephros development(+)
           |   |__regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(+)
           |__regulation of muscle cell apoptotic process
           |   |__negative regulation of muscle cell apoptotic process(+)
           |   |__positive regulation of muscle cell apoptotic process(+)
           |   |__regulation of smooth muscle cell apoptotic process(+)
           |   |__regulation of striated muscle cell apoptotic process(+)
           |__regulation of myeloid cell apoptotic process
           |   |__negative regulation of myeloid cell apoptotic process(+)
           |   |__positive regulation of myeloid cell apoptotic process(+)
           |   |__regulation of erythrocyte apoptotic process(+)
           |   |__regulation of macrophage apoptotic process(+)
           |   |__regulation of mast cell apoptotic process(+)
           |   |__regulation of neutrophil apoptotic process(+)
           |__regulation of myofibroblast cell apoptotic process
           |   |__negative regulation of myofibroblast cell apoptotic process
           |   |__positive regulation of myofibroblast cell apoptotic process
           |__regulation of neuron apoptotic process 33 rec.
               |__negative regulation of neuron apoptotic process(+) 22 rec.
               |__positive regulation of neuron apoptotic process(+) 10 rec.
               |__regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(+)
               |__regulation of hippocampal neuron apoptotic process(+)
               |__regulation of motor neuron apoptotic process(+) 1 rec.
               |__regulation of outer hair cell apoptotic process(+)
               |__regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(+)
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Is a regulation of programmed cell death
Part of
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Synonyms
  • "apoptosis regulator activity" RELATED
    "regulation of apoptosis" NARROW
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-169911 "Regulation of Apoptosis"
Reactome:R-HSA-5633008 "TP53 Regulates Transcription of Cell Death Genes"