FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term tRNA aminoacylation ID (Ontology) GO:0043039 (Gene Ontology)
Definition The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules.
Also Known As "aminoacyl-tRNA biosynthesis" ; "aminoacyl-tRNA biosynthetic process" ; "tRNA charging"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      10
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 tRNA aminoacylation (all annotations which use CV term, excluding "NOT" statements)      10
     involved_in | tRNA aminoacylation      10
Spanning Tree (Parents/Children)
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amino acid metabolic process
 |__amino acid activation___
RNA metabolic process       |
 |__tRNA metabolic process__|
                            tRNA aminoacylation  47 rec.
                             |__asparaginyl-tRNAAsn biosynthesis via transamidation
                             |__glutaminyl-tRNAGln biosynthesis via transamidation 4 rec.
                             |__tRNA aminoacylation for nonribosomal peptide biosynthetic process
                             |__tRNA aminoacylation for protein translation 43 rec.
                                 |__alanyl-tRNA aminoacylation(+) 3 rec.
                                 |__arginyl-tRNA aminoacylation(+) 3 rec.
                                 |__asparaginyl-tRNA aminoacylation(+) 2 rec.
                                 |__aspartyl-tRNA aminoacylation(+) 2 rec.
                                 |__cysteinyl-tRNA aminoacylation(+) 2 rec.
                                 |__glutaminyl-tRNA aminoacylation(+) 1 rec.
                                 |__glutamyl-tRNA aminoacylation(+) 2 rec.
                                 |__glycyl-tRNA aminoacylation(+) 1 rec.
                                 |__histidyl-tRNA aminoacylation(+) 1 rec.
                                 |__isoleucyl-tRNA aminoacylation(+) 2 rec.
                                 |__leucyl-tRNA aminoacylation(+) 2 rec.
                                 |__lysyl-tRNA aminoacylation(+) 1 rec.
                                 |__methionyl-tRNA aminoacylation(+) 2 rec.
                                 |__phenylalanyl-tRNA aminoacylation(+) 3 rec.
                                 |__prolyl-tRNA aminoacylation(+) 2 rec.
                                 |__seryl-tRNA aminoacylation(+) 3 rec.
                                 |__threonyl-tRNA aminoacylation(+) 1 rec.
                                 |__tRNA aminoacylation for mitochondrial protein translation(+) 6 rec.
                                 |__tryptophanyl-tRNA aminoacylation(+) 2 rec.
                                 |__tyrosyl-tRNA aminoacylation(+) 2 rec.
                                 |__valyl-tRNA aminoacylation(+) 2 rec.
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Is a tRNA metabolic process
amino acid activation
Part of
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Synonyms
  • "amino acid activation" RELATED
    "aminoacyl-tRNA biosynthesis" EXACT
    "aminoacyl-tRNA biosynthetic process" EXACT
    "tRNA charging" EXACT
Secondary IDs
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