FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term ATP-binding cassette (ABC) transporter complex ID (Ontology) GO:0043190 (Gene Ontology)
Definition A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.[ PubMed:11421269 PubMed:15111107 ]
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       6
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 ATP-binding cassette (ABC) transporter complex (all annotations which use CV term, excluding "NOT" statements)       6
     part_of | ATP-binding cassette (ABC) transporter complex       6
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plasma membrane
 |__plasma membrane protein complex___________________
membrane protein complex                              |
 |__plasma membrane protein complex___________________|
transmembrane transporter complex                     |
 |__ATPase dependent transmembrane transport complex__|
                                                      ATP-binding cassette (ABC) transporter complex  6 rec.
                                                       |__ATP-binding cassette (ABC) transporter complex, integrated substrate binding
                                                       |__ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
                                                       |__ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing
                                                       |__BtuCD complex
                                                       |__cobalamin transport complex
                                                       |__enzyme IIA-maltose transporter complex
                                                       |__glycerol-3-phosphate-transporting ATPase complex
                                                       |__maltose transport complex
                                                       |   |__MalFGK2 complex
                                                       |__methionine-importing ABC transporter complex
                                                       |__MsbA transporter complex
                                                       |__ProVWX complex
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Is a ATPase dependent transmembrane transport complex
plasma membrane protein complex
Part of
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Synonyms
  • "ABC-type efflux permease complex" NARROW
    "ABC-type efflux porter complex" NARROW
    "ABC-type uptake permease complex" NARROW
    "mating pheromone exporter" NARROW
Secondary IDs
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