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| Term | nuclear SCF ubiquitin ligase complex | ID (Ontology) | GO:0043224 (Gene Ontology) |
| Definition | A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).[ PubMed:15571813 PubMed:15688063 ] | ||
| Also Known As | "nuclear cullin complex" ; "nuclear SCF complex" ; "nuclear Skp1/Cul1/F-box protein complex" | ||
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ubiquitin ligase complex |__nuclear ubiquitin ligase complex__ cullin-RING ubiquitin ligase complex | |__SCF ubiquitin ligase complex______| nuclear protein-containing complex | |__nuclear ubiquitin ligase complex__| nuclear SCF ubiquitin ligase complex |
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nuclear ubiquitin ligase complex SCF ubiquitin ligase complex |
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