FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term cytotoxic T cell degranulation ID (Ontology) GO:0043316 (Gene Ontology)
Definition The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.[ ISBN:0781735149 ]
Also Known As "cytotoxic T cell granule exocytosis" ; "cytotoxic T lymphocyte degranulation" ; "cytotoxic T lymphocyte granule exocytosis" (for all, see Synonyms field below)
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Spanning Tree (Parents/Children)
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leukocyte mediated cytotoxicity
 |__T cell mediated cytotoxicity___________________
immune effector process                            |
 |__leukocyte degranulation________________________|
lymphocyte activation involved in immune response  |
 |__T cell activation involved in immune response__|
T cell mediated immunity                           |
 |__T cell mediated cytotoxicity___________________|
T cell activation                                  |
 |__T cell activation involved in immune response__|
regulated exocytosis                               |
 |__leukocyte degranulation________________________|
establishment of localization in cell              |
 |__leukocyte degranulation________________________|
                                                   cytotoxic T cell degranulation
                                                    |__regulation of cytotoxic T cell degranulation
                                                        |__negative regulation of cytotoxic T cell degranulation
                                                        |__positive regulation of cytotoxic T cell degranulation
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Is a leukocyte degranulation
Part of T cell mediated cytotoxicity
T cell activation involved in immune response
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Synonyms
  • "cytotoxic T cell granule exocytosis" EXACT
    "cytotoxic T lymphocyte degranulation" EXACT
    "cytotoxic T lymphocyte granule exocytosis" EXACT
    "cytotoxic T-cell degranulation" EXACT
    "cytotoxic T-cell granule exocytosis" EXACT
    "cytotoxic T-lymphocyte degranulation" EXACT
    "cytotoxic T-lymphocyte granule exocytosis" EXACT
Secondary IDs
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