FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term CD4-positive or CD8-positive, alpha-beta T cell lineage commitment ID (Ontology) GO:0043369 (Gene Ontology)
Definition The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells.[ ISBN:0781735149 ]
Also Known As "CD4-positive or CD8-positive, alpha-beta T lymphocyte lineage commitment" ; "CD4-positive or CD8-positive, alpha-beta T-cell lineage commitment" ; "CD4-positive or CD8-positive, alpha-beta T-lymphocyte lineage commitment" (for all, see Synonyms field below)
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Spanning Tree (Parents/Children)
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T cell differentiation
 |__T cell lineage commitment__
T cell selection               |
 |__positive T cell selection__|
cell fate commitment           |
 |__T cell lineage commitment__|
                               CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
                                |__CD4-positive, alpha-beta T cell lineage commitment
                                |   |__CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment
                                |   |__T-helper cell lineage commitment(+)
                                |__CD8-positive, alpha-beta T cell lineage commitment
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Is a T cell lineage commitment
Part of positive T cell selection
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Synonyms
  • "CD4-positive or CD8-positive, alpha-beta T lymphocyte lineage commitment" EXACT
    "CD4-positive or CD8-positive, alpha-beta T-cell lineage commitment" EXACT
    "CD4-positive or CD8-positive, alpha-beta T-lymphocyte lineage commitment" EXACT
    "CD4-positive/CD8-positive, alpha-beta T cell lineage commitment" EXACT
Secondary IDs
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