FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term corticotropin-releasing hormone secretion ID (Ontology) GO:0043396 (Gene Ontology)
Definition The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle.[ PubMed:11027914 ]
Also Known As "corticotropin-releasing factor secretion" ; "CRF secretion" ; "CRH secretion"
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peptide secretion__
hormone secretion__|
                   peptide hormone secretion
                    |__corticotropin-releasing hormone secretion
                        |__regulation of corticotropin-releasing hormone secretion
                            |__negative regulation of corticotropin-releasing hormone secretion
                            |__positive regulation of corticotropin-releasing hormone secretion
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Is a peptide hormone secretion
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Synonyms
  • "corticotropin-releasing factor secretion" EXACT
    "CRF secretion" EXACT
    "CRH secretion" EXACT
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