FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term Ku70:Ku80 complex ID (Ontology) GO:0043564 (Gene Ontology)
Definition Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.[ PubMed:12518983 ]
Also Known As "Ku70:Ku80 heterodimer"
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       3
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 Genes
 Ku70:Ku80 complex (all annotations which use CV term, excluding "NOT" statements)       3
     part_of | Ku70:Ku80 complex       2
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nucleus_____________________
protein-containing complex__|
                            nuclear protein-containing complex
                             |__Ku70:Ku80 complex  3 rec.
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Is a nuclear protein-containing complex
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