FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term nuclear DNA replication factor C complex ID (Ontology) GO:0043599 (Gene Ontology)
Definition A nuclear complex of five polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase delta or epsilon. In Saccharomyces and several other species, the subunits are known as Rfc1p-Rfc5p, although subunit names do not necessarily correspond between different species.[ PubMed:14614842 ]
Also Known As "nuclear RFC"
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nucleus
 |__nuclear protein-containing complex__
replication fork                        |
 |__DNA replication factor C complex____|
replisome                               |
 |__nuclear replisome___________________|
protein-containing complex              |
 |__DNA replication factor C complex____|
 |__nuclear protein-containing complex__|
nuclear replication fork                |
 |__nuclear replisome___________________|
nuclear protein-containing complex      |
 |__nuclear replisome___________________|
                                        nuclear DNA replication factor C complex
                                         |__DNA replication factor C core complex
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Is a DNA replication factor C complex
nuclear protein-containing complex
Part of nuclear replisome
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