FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term nuclear replisome ID (Ontology) GO:0043601 (Gene Ontology)
Definition A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.
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nuclear chromosome
 |__nuclear replication fork____________
nucleus                                 |
 |__nuclear protein-containing complex__|
replication fork                        |
 |__replisome___________________________|
 |__nuclear replication fork____________|
protein-containing complex              |
 |__nuclear protein-containing complex__|
protein-DNA complex                     |
 |__replisome___________________________|
                                        nuclear replisome  12 rec.
                                         |__alpha DNA polymerase:primase complex 5 rec.
                                         |__delta DNA polymerase complex 4 rec.
                                         |__DNA replication factor A complex 3 rec.
                                         |__nuclear DNA replication factor C complex
                                             |__DNA replication factor C core complex
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Is a replisome
nuclear protein-containing complex
Part of nuclear replication fork
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