FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term negative regulation of molecular function ID (Ontology) GO:0044092 (Gene Ontology)
Definition Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
Spanning Tree (Parents/Children)
Only view relationship: 
  biological regulation
   |__regulation of molecular function
       |__negative regulation of molecular function  2 rec.
           |__negative regulation of ATP-dependent activity
           |   |__negative regulation of ATPase-coupled calcium transmembrane transporter activity
           |   |__negative regulation of calcium-dependent ATPase activity
           |   |__negative regulation of helicase activity
           |   |__negative regulation of P-type sodium:potassium-exchanging transporter activity
           |__negative regulation of binding
           |   |__negative regulation of chromatin binding
           |   |__negative regulation of DNA binding(+)
           |   |__negative regulation of lipid binding
           |   |__negative regulation of protein binding(+)
           |__negative regulation of catalytic activity 2 rec.
           |   |__negative regulation of adenylate cyclase activity
           |   |__negative regulation of endoribonuclease activity
           |   |__negative regulation of glycogen (starch) synthase activity
           |   |__negative regulation of guanylate cyclase activity
           |   |__negative regulation of helicase activity
           |   |__negative regulation of hydrolase activity(+)
           |   |__negative regulation of kinase activity(+) 1 rec.
           |   |__negative regulation of oxidoreductase activity(+) 1 rec.
           |   |__negative regulation of polynucleotide adenylyltransferase activity
           |   |__negative regulation of protein ADP-ribosylation
           |   |__negative regulation of RNA-dependent RNA polymerase activity
           |   |__negative regulation of ubiquitin-protein transferase activity(+)
           |__negative regulation of DNA-binding transcription factor activity
           |   |__negative regulation of CREB transcription factor activity
           |   |__negative regulation of NF-kappaB transcription factor activity
           |__negative regulation of guanyl-nucleotide exchange factor activity
           |   |__negative regulation of Rho guanyl-nucleotide exchange factor activity
           |__negative regulation of signaling receptor activity
           |   |__cross-receptor inhibition within G protein-coupled receptor heterodimer
           |   |__negative regulation of corticotropin-releasing hormone receptor activity
           |   |__negative regulation of epidermal growth factor-activated receptor activity
           |   |__negative regulation of NMDA glutamate receptor activity
           |__negative regulation of transporter activity
               |__negative regulation of ion transmembrane transporter activity(+)
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a regulation of molecular function
Part of
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts