FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term Dsc E3 ubiquitin ligase complex ID (Ontology) GO:0044695 (Gene Ontology)
Definition An E3 ubiquitin ligase complex localized to the ER and Golgi membrane. In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism.[ PubMed:21504829 ]
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membrane
 |__organelle membrane____________________
 |__membrane protein complex______________|
protein-containing complex                |
 |__membrane protein complex______________|
membrane-bounded organelle                |
 |__organelle membrane____________________|
intracellular protein-containing complex  |
 |__ubiquitin ligase complex______________|
transferase complex                       |
 |__ubiquitin ligase complex______________|
                                          Dsc E3 ubiquitin ligase complex
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Is a ubiquitin ligase complex
membrane protein complex
Part of organelle membrane
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