FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term T cell selection ID (Ontology) GO:0045058 (Gene Ontology)
Definition The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation.[ ISBN:0781735149 PubMed:12414722 ]
Also Known As "T lymphocyte selection" ; "T-cell selection" ; "T-lymphocyte selection"
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biological_process
 |__immune system process___
lymphocyte differentiation  |
 |__T cell differentiation__|
T cell activation           |
 |__T cell differentiation__|
                            T cell selection
                             |__beta selection
                             |__extrathymic T cell selection
                             |   |__negative extrathymic T cell selection
                             |   |__positive extrathymic T cell selection
                             |__negative T cell selection
                             |   |__negative extrathymic T cell selection
                             |   |__negative thymic T cell selection
                             |__positive T cell selection
                             |   |__CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(+)
                             |   |__positive extrathymic T cell selection
                             |   |__positive thymic T cell selection(+)
                             |__thymic T cell selection
                                 |__negative thymic T cell selection
                                 |__positive thymic T cell selection(+)
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Is a immune system process
Part of T cell differentiation
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Synonyms
  • "T lymphocyte selection" EXACT
    "T-cell selection" EXACT
    "T-lymphocyte selection" EXACT
Secondary IDs
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Wikipedia:Thymocyte