FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term cell fate commitment ID (Ontology) GO:0045165 (Gene Ontology)
Definition The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate.[ ISBN:0716731185 ]
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      26
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 cell fate commitment (all annotations which use CV term, excluding "NOT" statements)      26
     involved_in | cell fate commitment      26
Spanning Tree (Parents/Children)
Only view relationship:
cellular process
 |__cellular developmental process__
developmental process               |
 |__cellular developmental process__|
cellular developmental process      |
 |__cell differentiation____________|
                                    cell fate commitment  335 rec.
                                     |__apical cell fate commitment
                                     |__asymmetric neuroblast division 39 rec.
                                     |   |__asymmetric neuroblast division resulting in ganglion mother cell formation 2 rec.
                                     |   |__establishment or maintenance of neuroblast polarity(+) 13 rec.
                                     |__B cell lineage commitment
                                     |   |__B-1 B cell lineage commitment
                                     |__cardiac cell fate commitment 17 rec.
                                     |   |__cardiac cell fate determination(+) 3 rec.
                                     |   |__cardiac cell fate specification(+) 9 rec.
                                     |   |__cardiac fibroblast cell fate commitment(+)
                                     |   |__cardiac glial cell fate commitment(+)
                                     |   |__cardiac muscle cell fate commitment(+)
                                     |   |__cardiac neuron fate commitment
                                     |   |__cardiac vascular smooth muscle cell fate commitment(+)
                                     |   |__cardioblast cell fate commitment(+) 13 rec.
                                     |   |__dorsal vessel aortic cell fate commitment 1 rec.
                                     |   |__dorsal vessel heart proper cell fate commitment 2 rec.
                                     |   |__endocardial cell fate commitment(+)
                                     |   |__His-Purkinje system cell fate commitment
                                     |__cell fate commitment involved in formation of primary germ layer 17 rec.
                                     |   |__ectodermal cell fate commitment(+) 3 rec.
                                     |   |__endodermal cell fate commitment(+) 1 rec.
                                     |   |__mesodermal cell fate commitment(+) 14 rec.
                                     |__cell fate commitment involved in pattern specification 35 rec.
                                     |   |__cell fate determination involved in pattern specification(+) 22 rec.
                                     |   |__cell fate specification involved in pattern specification(+) 8 rec.
                                     |   |__dorsal vessel aortic cell fate commitment 1 rec.
                                     |   |__dorsal vessel heart proper cell fate commitment 2 rec.
                                     |   |__eye field cell fate commitment involved in camera-type eye formation
                                     |   |__ventral spinal cord interneuron fate commitment(+)
                                     |__cell fate determination 133 rec.
                                     |   |__asymmetric protein localization involved in cell fate determination(+) 18 rec.
                                     |   |__branched duct epithelial cell fate determination, open tracheal system
                                     |   |__cardiac cell fate determination(+) 3 rec.
                                     |   |__cell fate determination involved in pattern specification(+) 22 rec.
                                     |   |__compound eye cone cell fate determination
                                     |   |__ectodermal cell fate determination 2 rec.
                                     |   |__endodermal cell fate determination 1 rec.
                                     |   |__endothelial cell fate determination
                                     |   |__eosinophil fate determination
                                     |   |__epithelial cell fate determination, open tracheal system 3 rec.
                                     |   |__ganglion mother cell fate determination 7 rec.
                                     |   |__glial cell fate determination 3 rec.
                                     |   |__leading edge cell fate determination(+)
                                     |   |__mesodermal cell fate determination(+) 3 rec.
                                     |   |__muscle cell fate determination(+) 5 rec.
                                     |   |__myoblast fate determination(+)
                                     |   |__neuroblast fate determination 27 rec.
                                     |   |__neuron fate determination(+) 9 rec.
                                     |   |__oocyte fate determination(+) 34 rec.
                                     |   |__pole cell fate determination 4 rec.
                                     |   |__regulation of cell fate determination(+) 1 rec.
                                     |   |__stem cell fate determination(+) 1 rec.
                                     |   |__vulval cell fate determination
                                     |__cell fate specification 107 rec.
                                     |   |__abaxial cell fate specification
                                     |   |__anther wall tapetum cell fate specification
                                     |   |__bundle sheath cell fate specification
                                     |   |__cardiac cell fate specification(+) 9 rec.
                                     |   |__cell fate specification involved in pattern specification(+) 8 rec.
                                     |   |__compound eye cone cell fate specification(+) 5 rec.
                                     |   |__ectodermal cell fate specification(+) 1 rec.
                                     |   |__endodermal cell fate specification(+)
                                     |   |__endothelial cell fate specification(+)
                                     |   |__eosinophil fate specification
                                     |   |__epidermal cell fate specification(+) 2 rec.
                                     |   |__epithelial cell type specification, open tracheal system(+) 9 rec.
                                     |   |__glial cell fate specification(+)
                                     |   |__mesodermal cell fate specification(+) 5 rec.
                                     |   |__muscle cell fate specification(+) 7 rec.
                                     |   |__myoblast fate specification(+) 3 rec.
                                     |   |__neuroblast fate specification 4 rec.
                                     |   |__neuron fate specification(+) 31 rec.
                                     |   |__plant endodermal cell fate specification
                                     |   |__plant epidermal cell fate specification(+)
                                     |   |__regulation of cell fate specification(+) 27 rec.
                                     |   |__skeletal muscle satellite cell fate specification
                                     |   |__stem cell fate specification(+)
                                     |   |__vulval cell fate specification
                                     |__cell-cell signaling involved in cell fate commitment 11 rec.
                                     |   |__lateral inhibition 11 rec.
                                     |   |__trichome patterning(+)
                                     |__compound eye cone cell fate commitment 6 rec.
                                     |   |__compound eye cone cell fate determination
                                     |   |__compound eye cone cell fate specification(+) 5 rec.
                                     |__DCT cell fate commitment
                                     |   |__metanephric DCT cell fate commitment
                                     |__determination of imaginal disc primordium 11 rec.
                                     |   |__determination of genital disc primordium 10 rec.
                                     |   |__determination of wing disc primordium 1 rec.
                                     |__eosinophil fate commitment
                                     |   |__eosinophil fate determination
                                     |   |__eosinophil fate specification
                                     |__epithelial cell fate commitment
                                     |   |__endothelial cell fate commitment(+)
                                     |   |__glomerular parietal epithelial cell fate commitment(+)
                                     |   |__granulosa cell fate commitment
                                     |   |__leading edge cell fate commitment(+)
                                     |   |__pancreatic A cell fate commitment
                                     |   |__pancreatic D cell fate commitment
                                     |   |__pancreatic PP cell fate commitment
                                     |   |__podocyte cell fate commitment(+)
                                     |   |__Sertoli cell fate commitment
                                     |   |__type B pancreatic cell fate commitment
                                     |__glial cell fate commitment 3 rec.
                                     |   |__astrocyte fate commitment(+)
                                     |   |__cardiac glial cell fate commitment(+)
                                     |   |__glial cell fate determination 3 rec.
                                     |   |__glial cell fate specification(+)
                                     |   |__oligodendrocyte cell fate commitment(+)
                                     |   |__radial glial cell fate commitment in forebrain
                                     |__guard cell fate commitment
                                     |__hypothalamus gonadotrophin-releasing hormone neuron fate commitment
                                     |__inner cell mass cell fate commitment
                                     |__juxtaglomerulus cell fate commitment
                                     |   |__mesonephric juxtaglomerulus cell fate commitment
                                     |   |__metanephric juxtaglomerulus cell fate commitment
                                     |__lens fiber cell fate commitment
                                     |__mesangial cell fate commitment
                                     |   |__glomerular mesangial cell fate commitment(+)
                                     |__mesenchymal cell fate commitment
                                     |__muscle cell fate commitment 14 rec.
                                     |   |__cardiac muscle cell fate commitment(+)
                                     |   |__muscle cell fate determination(+) 5 rec.
                                     |   |__muscle cell fate specification(+) 7 rec.
                                     |   |__vascular associated smooth muscle cell fate commitment(+)
                                     |__myoblast fate commitment 3 rec.
                                     |   |__myoblast fate commitment in head
                                     |   |__myoblast fate commitment in trunk
                                     |   |__myoblast fate commitment involved in skeletal muscle regeneration(+)
                                     |   |__myoblast fate determination(+)
                                     |   |__myoblast fate specification(+) 3 rec.
                                     |__neuroblast fate commitment 35 rec.
                                     |   |__asymmetric neuroblast division resulting in ganglion mother cell formation 2 rec.
                                     |   |__neuroblast fate determination 27 rec.
                                     |   |__neuroblast fate specification 4 rec.
                                     |__neuron fate commitment 110 rec.
                                     |   |__cardiac neuron fate commitment
                                     |   |__cerebral cortex GABAergic interneuron fate commitment
                                     |   |__forebrain neuron fate commitment(+)
                                     |   |__inner ear receptor cell fate commitment(+)
                                     |   |__neuron fate determination(+) 9 rec.
                                     |   |__neuron fate specification(+) 31 rec.
                                     |   |__noradrenergic neuron fate commitment(+)
                                     |   |__olfactory bulb interneuron fate commitment
                                     |   |__pancreatic D cell fate commitment
                                     |   |__photoreceptor cell fate commitment(+) 96 rec.
                                     |   |__somatic motor neuron fate commitment(+)
                                     |   |__subpallium neuron fate commitment
                                     |   |__ventral spinal cord interneuron fate commitment(+)
                                     |__oocyte fate commitment 2 rec.
                                     |__osteoblast fate commitment
                                     |__pancreatic E cell fate commitment
                                     |__pro-T cell lineage commitment
                                     |__proximal convoluted tubule segment 1 cell fate commitment
                                     |__regulation of cell fate commitment 33 rec.
                                     |   |__negative regulation of cell fate commitment(+) 21 rec.
                                     |   |__positive regulation of cell fate commitment(+)
                                     |   |__regulation of cell fate specification(+) 27 rec.
                                     |   |__regulation of R7 cell fate commitment(+)
                                     |   |__regulation of retinal cone cell fate commitment(+)
                                     |   |__regulation of retinal rod cell fate commitment(+)
                                     |   |__regulation of T-helper 17 cell lineage commitment(+)
                                     |   |__regulation of venous endothelial cell fate commitment(+)
                                     |__renal interstitial fibroblast fate commitment
                                     |   |__mesonephric interstitial fibroblast fate commitment
                                     |   |__metanephric interstitial fibroblast fate commitment
                                     |__seed trichome initiation
                                     |__skeletal muscle satellite cell commitment
                                     |   |__skeletal muscle satellite cell fate determination
                                     |   |__skeletal muscle satellite cell fate specification
                                     |__stem cell fate commitment 6 rec.
                                     |   |__neural crest cell fate commitment(+)
                                     |   |__stem cell fate determination(+) 1 rec.
                                     |   |__stem cell fate specification(+)
                                     |__T cell lineage commitment
                                     |   |__alpha-beta T cell lineage commitment(+)
                                     |   |__CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(+)
                                     |   |__gamma-delta T cell lineage commitment
                                     |__trophectodermal cell fate commitment
                                     |__vulval cell fate commitment
                                         |__vulval cell fate determination
                                         |__vulval cell fate specification
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a cellular developmental process
Part of cell differentiation
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts