FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term synapse ID (Ontology) GO:0045202 (Gene Ontology)
Definition The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.[ ISBN:0198506732 PubMed:24619342 PubMed:29383328 PubMed:31998110 ]
Also Known As "synaptic junction"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN     286
Genes (FBgn)  GO_CELLULAR_COMPONENT      91
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN     119
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Constructs
 synapse (all annotations which use CV term, excluding "NOT" statements)     286     97    119
     is_active_in | synapse       --      44       --
     located_in | synapse       --      52       --
     synapse | adult stage      44       --      28
     synapse | adult stage | decreased number       7       --       5
     synapse | adult stage | increased number       6       --       5
     synapse | adult stage | increased number | somatic clone - tissue specific       2       --       --
     synapse | decreased number       1       --       --
     synapse | decreased number | larval stage       7       --       --
     synapse | ectopic      27       --      14
     synapse | ectopic | heat sensitive       3       --       --
     synapse | ectopic | increased number       2       --       2
     synapse | embryonic stage       4       --       2
     synapse | heat sensitive       3       --       --
     synapse | increased number       7       --       6
     synapse | increased number | wandering third instar larval stage       1       --       --
     synapse | larval stage      32       --      15
     synapse | P-stage | increased number       2       --       --
     synapse | progressive | somatic clone       1       --       --
     synapse | RU486 conditional       3       --       3
     synapse | somatic clone       1       --       --
     synapse | temperature conditional       1       --       --
     synapse | wandering third instar larval stage       2       --       --
     synapse | wandering third instar larval stage | conditional       2       --       --
Spanning Tree (Parents/Children)
Only view relationship:
  cellular anatomical structure
   |__cell junction
       |__synapse  1282 rec.
           |__cerebellar Golgi cell to granule cell synapse
           |__cholinergic synapse 1 rec.
           |   |__neuromuscular junction of skeletal muscle fiber
           |__dopaminergic synapse 1 rec.
           |__excitatory synapse 1 rec.
           |   |__asymmetric, glutamatergic, excitatory synapse(+)
           |   |__excitatory neuromuscular junction(+)
           |   |__parallel fiber to Purkinje cell synapse
           |__GABA-ergic synapse
           |   |__symmetric, GABA-ergic, inhibitory synapse
           |__glutamatergic synapse 6 rec.
           |   |__asymmetric, glutamatergic, excitatory synapse(+)
           |__glycinergic synapse
           |__inhibitory synapse
           |   |__inhibitory neuromuscular junction(+)
           |   |__symmetric, GABA-ergic, inhibitory synapse
           |__neuromuscular junction 521 rec.
           |   |__excitatory neuromuscular junction(+)
           |   |__inhibitory neuromuscular junction(+)
           |   |__neuromuscular junction of myotube(+)
           |   |__neuromuscular junction of somatic muscle(+) 3 rec.
           |__neuron to neuron synapse 41 rec.
           |   |__asymmetric synapse(+) 41 rec.
           |   |__hippocampal mossy fiber to CA3 synapse
           |   |__symmetric synapse(+)
           |__noradrenergic synapse
           |__perforant pathway to dendrate granule cell synapse
           |__polyadic synapse
           |__ribbon synapse
           |   |__cochlear hair cell ribbon synapse
           |   |__photoreceptor ribbon synapse
           |__Schaffer collateral - CA1 synapse
           |__serotonergic synapse
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Is a cell junction
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Synonyms
  • "electrotonic synapse" RELATED
    "mixed synapse" NARROW
    "synaptic junction" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
NIF_Subcellular:sao914572699
Wikipedia:Chemical_synapse