|
General Information
|
| Term |
pyruvate dehydrogenase complex |
ID (Ontology) |
GO:0045254 (Gene Ontology) |
| Definition |
A multi-enzyme complex that catalyzes the oxidative decarboxylation of pyruvate to form acetyl-CoA. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: pyruvate dehydrogenase (E1, which may be a homodimer or a heterotetramer of two alpha and two beta subunits, depending on species), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Additional proteins may also be present.[ PubMed:36863425 ] |
| Also Known As |
"pyruvate dehydrogenase complex (lipoamide)" |
| Comment |
|
|
Links to External Ontologies
|
|
QuickGO data AmiGO data
|
|
Annotations
|
|
Records annotated with this term OR any of its CHILD TERMS
|
|
|
|
Records annotated with this exact term (annotations to child terms are NOT included)
|
| Data Class | Field | Records |
|---|
|
| Genes (FBgn) | GO_CELLULAR_COMPONENT | 8 |
|
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
|
| Full annotation statements | Relevant FlyBase reports |
|---|
| Gene Groups | Genes |
|---|
pyruvate dehydrogenase complex (all annotations which use CV term, excluding "NOT" statements) | 4 | 8 | part_of | pyruvate dehydrogenase complex | -- | 8 |
|
Relationships
