FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term leukocyte activation ID (Ontology) GO:0045321 (Gene Ontology)
Definition A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
Also Known As "immune cell activation" ; "leucocyte activation"
Comment
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  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 leukocyte activation (all annotations which use CV term, excluding "NOT" statements)       2
     involved_in | leukocyte activation       2
Spanning Tree (Parents/Children)
Only view relationship:
biological_process
 |__immune system process_________
cellular process                  |
 |__cell activation_______________|
multicellular organismal process  |
 |__cell activation_______________|
                                  leukocyte activation  2 rec.
                                   |__leukocyte activation involved in immune response
                                   |   |__basophil activation involved in immune response(+)
                                   |   |__lymphocyte activation involved in immune response(+)
                                   |   |__macrophage activation involved in immune response(+)
                                   |   |__myeloid cell activation involved in immune response(+)
                                   |   |__plasmacytoid dendritic cell activation involved in immune response(+)
                                   |__leukocyte activation involved in inflammatory response
                                   |   |__microglial cell activation(+)
                                   |__leukocyte adhesive activation
                                   |__lymphocyte activation
                                   |   |__B cell activation(+)
                                   |   |__establishment of lymphocyte polarity(+)
                                   |   |__immunological synapse formation(+)
                                   |   |__lymphocyte activation involved in immune response(+)
                                   |   |__lymphocyte differentiation(+)
                                   |   |__lymphocyte proliferation(+)
                                   |   |__natural killer cell activation(+)
                                   |   |__regulation of lymphocyte activation(+)
                                   |   |__T cell activation(+)
                                   |__myeloid leukocyte activation
                                   |   |__granulocyte activation(+)
                                   |   |__macrophage activation(+)
                                   |   |__mast cell activation(+)
                                   |   |__monocyte activation(+)
                                   |   |__myeloid cell activation involved in immune response(+)
                                   |   |__myeloid dendritic cell activation(+)
                                   |__plasmacytoid dendritic cell activation
                                   |   |__plasmacytoid dendritic cell activation involved in immune response(+)
                                   |   |__plasmacytoid dendritic cell differentiation(+)
                                   |__regulation of leukocyte activation
                                       |__negative regulation of leukocyte activation(+)
                                       |__positive regulation of leukocyte activation(+)
                                       |__regulation of eosinophil activation(+)
                                       |__regulation of lymphocyte activation(+)
                                       |__regulation of macrophage activation(+)
                                       |__regulation of mast cell activation(+)
                                       |__regulation of myeloid dendritic cell activation(+)
                                       |__regulation of neutrophil activation(+)
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Is a cell activation
immune system process
Part of
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Synonyms
  • "immune cell activation" EXACT
    "leucocyte activation" EXACT
Secondary IDs
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Wikipedia:Immunologic_activation