FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term phospholipid translocation ID (Ontology) GO:0045332 (Gene Ontology)
Definition The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.[ ISBN:0815316194 PubMed:16452632 PubMed:20043909 PubMed:20302864 ]
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      11
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 phospholipid translocation (all annotations which use CV term, excluding "NOT" statements)       3     11
     involved_in | phospholipid translocation       --      11
Spanning Tree (Parents/Children)
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lipid transport
 |__phospholipid transport_________________
 |__lipid translocation____________________|
organophosphate ester transport            |
 |__phospholipid transport_________________|
regulation of membrane lipid distribution  |
 |__lipid translocation____________________|
                                           phospholipid translocation  20 rec.
                                            |__aminophospholipid translocation
                                            |__lysophospholipid translocation
                                            |__plasma membrane phospholipid scrambling 8 rec.
                                            |   |__calcium activated phospholipid scrambling(+)
                                            |   |__phosphatidylserine exposure on apoptotic cell surface(+) 2 rec.
                                            |   |__phosphatidylserine exposure on blood platelet
                                            |   |__phosphatidylserine exposure on osteoblast involved in bone mineralization
                                            |__regulation of phospholipid translocation
                                                |__negative regulation of phospholipid translocation(+)
                                                |__positive regulation of phospholipid translocation(+)
                                                |__regulation of phosphatidylserine exposure on apoptotic cell surface(+)
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Is a phospholipid transport
lipid translocation
Part of
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Synonyms
  • "flippase" RELATED
    "phospholipid scrambling" RELATED
Secondary IDs
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Reactome:R-HSA-1660502 "PIPs transport between early and late endosome membranes"
Reactome:R-HSA-1660508 "PIPs transport between late endosome and Golgi membranes"
Reactome:R-HSA-1660510 "PIPs transport between Golgi and plasma membranes"
Reactome:R-HSA-1660524 "PIPs transport between plasma and early endosome membranes"
Reactome:R-HSA-1660537 "PIPs transport between early endosome and Golgi membranes"