FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term endothelial cell differentiation ID (Ontology) GO:0045446 (Gene Ontology)
Definition The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
Spanning Tree (Parents/Children)
Only view relationship: 
cell differentiation
 |__epithelial cell differentiation__
epithelium development               |
 |__endothelium development__________|
 |__epithelial cell differentiation__|
                                     endothelial cell differentiation  1 rec.
                                      |__blood vessel endothelial cell differentiation
                                      |   |__arterial endothelial cell differentiation(+)
                                      |   |__blood vessel endothelial cell fate commitment(+)
                                      |   |__cardiac blood vessel endothelial cell differentiation
                                      |   |__regulation of blood vessel endothelial cell differentiation(+)
                                      |   |__venous endothelial cell differentiation(+)
                                      |__cardiac endothelial cell differentiation
                                      |   |__cardiac blood vessel endothelial cell differentiation
                                      |   |__endocardial cell differentiation(+)
                                      |   |__epicardium-derived cardiac endothelial cell differentiation
                                      |__endothelial cell development 1 rec.
                                      |   |__endocardial cell development
                                      |   |__endothelial cell morphogenesis
                                      |   |__establishment of blood-nerve barrier
                                      |   |__establishment of endothelial barrier(+) 1 rec.
                                      |   |__regulation of endothelial cell development(+)
                                      |__endothelial cell fate commitment
                                      |   |__blood vessel endothelial cell fate commitment(+)
                                      |   |__endocardial cell fate commitment(+)
                                      |   |__endothelial cell fate determination
                                      |   |__endothelial cell fate specification(+)
                                      |   |__lymphatic endothelial cell fate commitment(+)
                                      |__lymphatic endothelial cell differentiation
                                      |   |__lymphatic endothelial cell fate commitment(+)
                                      |__regulation of endothelial cell differentiation
                                          |__negative regulation of endothelial cell differentiation(+)
                                          |__positive regulation of endothelial cell differentiation(+)
                                          |__regulation of blood vessel endothelial cell differentiation(+)
                                          |__regulation of endothelial cell development(+)
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a epithelial cell differentiation
Part of endothelium development
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts