FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term mast cell activation ID (Ontology) GO:0045576 (Gene Ontology)
Definition The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.[ ISBN:0781735149 ]
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  leukocyte activation
   |__myeloid leukocyte activation
       |__mast cell activation
           |__mast cell activation involved in immune response
           |   |__mast cell degranulation(+)
           |   |__regulation of mast cell activation involved in immune response(+)
           |__regulation of mast cell activation
               |__negative regulation of mast cell activation(+)
               |__positive regulation of mast cell activation(+)
               |__regulation of mast cell activation involved in immune response(+)
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Is a myeloid leukocyte activation
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