FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term negative regulation of DNA-templated transcription ID (Ontology) GO:0045892 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
Also Known As "down regulation of transcription, DNA-dependent" ; "down-regulation of transcription, DNA-dependent" ; "downregulation of transcription, DNA-dependent" (for all, see Synonyms field below)
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS     133
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 negative regulation of DNA-templated transcription (all annotations which use CV term, excluding "NOT" statements)       3    133
     involved_in | negative regulation of DNA-templated transcription       --     133
Spanning Tree (Parents/Children)
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DNA-templated transcription
 |__regulation of DNA-templated transcription______________
regulation of gene expression                              |
 |__regulation of DNA-templated transcription______________|
negative regulation of macromolecule biosynthetic process  |
 |__negative regulation of RNA biosynthetic process________|
negative regulation of RNA metabolic process               |
 |__negative regulation of RNA biosynthetic process________|
regulation of RNA biosynthetic process                     |
 |__regulation of DNA-templated transcription______________|
 |__negative regulation of RNA biosynthetic process________|
                                                           negative regulation of DNA-templated transcription  322 rec.
                                                            |__carbon catabolite repression of transcription
                                                            |   |__carbon catabolite repression of transcription by galactose(+)
                                                            |   |__carbon catabolite repression of transcription by glucose(+)
                                                            |   |__carbon catabolite repression of transcription from RNA polymerase II promoter(+)
                                                            |__negative regulation of antisense RNA transcription
                                                            |__negative regulation of DNA-templated transcription initiation 1 rec.
                                                            |   |__negative regulation of transcription initiation by RNA polymerase II(+) 1 rec.
                                                            |__negative regulation of DNA-templated transcription, elongation 14 rec.
                                                            |   |__negative regulation of transcription elongation by RNA polymerase I
                                                            |   |__negative regulation of transcription elongation by RNA polymerase II 10 rec.
                                                            |__negative regulation of lncRNA transcription
                                                            |__negative regulation of mating-type specific transcription, DNA-templated
                                                            |__negative regulation of miRNA transcription
                                                            |__negative regulation of mitochondrial transcription
                                                            |__negative regulation of termination of DNA-templated transcription
                                                            |   |__negative regulation of termination of RNA polymerase I transcription
                                                            |   |__negative regulation of termination of RNA polymerase II transcription(+)
                                                            |   |__transcription antitermination
                                                            |__negative regulation of transcription by competitive promoter binding
                                                            |__negative regulation of transcription by RNA polymerase I 1 rec.
                                                            |   |__negative regulation of termination of RNA polymerase I transcription
                                                            |   |__negative regulation of transcription elongation by RNA polymerase I
                                                            |   |__negative regulation of transcription of nucleolar large rRNA by RNA polymerase I 1 rec.
                                                            |__negative regulation of transcription by RNA polymerase II 225 rec.
                                                            |   |__carbon catabolite repression of transcription from RNA polymerase II promoter(+)
                                                            |   |__negative regulation of ribosomal protein gene transcription by RNA polymerase II(+)
                                                            |   |__negative regulation of snRNA transcription by RNA polymerase II
                                                            |   |__negative regulation of termination of RNA polymerase II transcription(+)
                                                            |   |__negative regulation of transcription initiation by RNA polymerase II(+) 1 rec.
                                                            |__negative regulation of transcription by RNA polymerase III 2 rec.
                                                            |__negative regulation of transcription by RNA polymerase V
                                                            |__negative regulation of transcription by transcription factor catabolism
                                                            |__nitrogen catabolite repression of transcription
                                                                |__nitrogen catabolite repression of transcription from RNA polymerase II promoter
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Is a regulation of DNA-templated transcription
negative regulation of RNA biosynthetic process
Part of
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Synonyms
  • "down regulation of gene-specific transcription" RELATED
    "down regulation of transcription, DNA-dependent" EXACT
    "down-regulation of gene-specific transcription" RELATED
    "down-regulation of transcription, DNA-dependent" EXACT
    "downregulation of gene-specific transcription" RELATED
    "downregulation of transcription, DNA-dependent" EXACT
    "inhibition of gene-specific transcription" RELATED
    "inhibition of transcription, DNA-dependent" NARROW
    "negative regulation of cellular transcription, DNA-dependent" EXACT
    "negative regulation of gene-specific transcription" RELATED
    "negative regulation of transcription, DNA-dependent" EXACT
    "negative regulation of transcription, DNA-templated" EXACT
    "transcription repressor activity" RELATED
Secondary IDs
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