FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term negative regulation of mitotic cell cycle ID (Ontology) GO:0045930 (Gene Ontology)
Definition Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.
Also Known As "down regulation of progression through mitotic cell cycle" ; "down-regulation of progression through mitotic cell cycle" ; "downregulation of progression through mitotic cell cycle" (for all, see Synonyms field below)
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       3
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 negative regulation of mitotic cell cycle (all annotations which use CV term, excluding "NOT" statements)       3
     involved_in | negative regulation of mitotic cell cycle       3
Spanning Tree (Parents/Children)
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negative regulation of cellular process
 |__negative regulation of cell cycle__
regulation of cell cycle               |
 |__regulation of mitotic cell cycle___|
 |__negative regulation of cell cycle__|
                                       negative regulation of mitotic cell cycle  69 rec.
                                        |__cell cycle switching, mitotic to meiotic cell cycle 4 rec.
                                        |   |__germline cell cycle switching, mitotic to meiotic cell cycle 4 rec.
                                        |__mitotic cell cycle checkpoint signaling 45 rec.
                                        |   |__mitotic cell size control checkpoint signaling(+)
                                        |   |__mitotic cytokinesis checkpoint signaling 1 rec.
                                        |   |__mitotic DNA integrity checkpoint signaling(+) 29 rec.
                                        |   |__mitotic G1/S transition checkpoint signaling(+) 3 rec.
                                        |   |__mitotic G2/M transition checkpoint(+) 20 rec.
                                        |   |__mitotic morphogenesis checkpoint signaling
                                        |   |__mitotic spindle checkpoint signaling(+) 13 rec.
                                        |   |__signal transduction involved in cytokinesis checkpoint
                                        |__mitotic cell cycle G1 arrest in response to pheromone
                                        |__negative regulation of mitotic cell cycle DNA replication
                                        |   |__negative regulation of mitotic DNA replication initiation(+)
                                        |__negative regulation of mitotic cell cycle phase transition 55 rec.
                                        |   |__mitotic cell size control checkpoint signaling(+)
                                        |   |__negative regulation of exit from mitosis(+)
                                        |   |__negative regulation of G1/S transition of mitotic cell cycle(+) 15 rec.
                                        |   |__negative regulation of G2/M transition of mitotic cell cycle(+) 27 rec.
                                        |   |__negative regulation of mitotic metaphase/anaphase transition(+) 13 rec.
                                        |__negative regulation of mitotic cell cycle, embryonic
                                        |   |__negative regulation of preblastoderm mitotic cell cycle
                                        |   |__negative regulation of syncytial blastoderm mitotic cell cycle
                                        |__negative regulation of mitotic nuclear division 16 rec.
                                            |__negative regulation of mitotic metaphase/anaphase transition(+) 13 rec.
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Is a regulation of mitotic cell cycle
negative regulation of cell cycle
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Synonyms
  • "down regulation of progression through mitotic cell cycle" EXACT
    "down-regulation of progression through mitotic cell cycle" EXACT
    "downregulation of progression through mitotic cell cycle" EXACT
    "inhibition of progression through mitotic cell cycle" NARROW
    "negative regulation of mitotic cell cycle progression" EXACT
    "negative regulation of progression through mitotic cell cycle" EXACT
Secondary IDs
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Reactome:R-HSA-8854050 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"