FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term negative regulation of nucleobase-containing compound metabolic process ID (Ontology) GO:0045934 (Gene Ontology)
Definition Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
Also Known As "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" (for all, see Synonyms field below)
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nucleobase-containing compound metabolic process
 |__regulation of nucleobase-containing compound metabolic process__
regulation of metabolic process                                     |
 |__negative regulation of metabolic process________________________|
negative regulation of cellular process                             |
 |__negative regulation of metabolic process________________________|
regulation of primary metabolic process                             |
 |__regulation of nucleobase-containing compound metabolic process__|
                                                                    negative regulation of nucleobase-containing compound metabolic process  383 rec.
                                                                     |__negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA
                                                                     |__negative regulation of butyryl-CoA catabolic process to butanol
                                                                     |__negative regulation of butyryl-CoA catabolic process to butyrate
                                                                     |__negative regulation of DNA metabolic process 44 rec.
                                                                     |   |__negative regulation of DNA biosynthetic process(+)
                                                                     |   |__negative regulation of DNA catabolic process(+)
                                                                     |   |__negative regulation of DNA recombination(+) 28 rec.
                                                                     |   |__negative regulation of DNA repair(+) 2 rec.
                                                                     |   |__negative regulation of DNA replication(+) 14 rec.
                                                                     |   |__negative regulation of meiotic DNA double-strand break formation(+)
                                                                     |   |__negative regulation of mitochondrial DNA metabolic process(+) 1 rec.
                                                                     |   |__negative regulation of mitotic recombination-dependent replication fork processing
                                                                     |   |__negative regulation of t-circle formation 1 rec.
                                                                     |   |__negative regulation of telomere maintenance(+)
                                                                     |__negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway
                                                                     |__negative regulation of nucleoside metabolic process
                                                                     |__negative regulation of nucleotide metabolic process 1 rec.
                                                                     |   |__negative regulation of nucleotide biosynthetic process(+)
                                                                     |   |__negative regulation of nucleotide catabolic process(+) 1 rec.
                                                                     |   |__negative regulation of purine nucleotide metabolic process(+) 1 rec.
                                                                     |__negative regulation of purine nucleobase metabolic process
                                                                     |__negative regulation of pyrimidine nucleobase metabolic process
                                                                     |__negative regulation of pyruvate decarboxylation to acetyl-CoA
                                                                     |__negative regulation of RNA metabolic process 340 rec.
                                                                     |   |__negative regulation of miRNA metabolic process(+)
                                                                     |   |__negative regulation of mRNA metabolic process(+) 15 rec.
                                                                     |   |__negative regulation of RNA biosynthetic process(+) 322 rec.
                                                                     |   |__negative regulation of RNA catabolic process(+) 14 rec.
                                                                     |   |__negative regulation of rRNA processing
                                                                     |   |__negative regulation of snoRNA metabolic process(+)
                                                                     |   |__negative regulation of snRNA pseudouridine synthesis
                                                                     |   |__negative regulation of tRNA metabolic process(+) 1 rec.
                                                                     |__negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA
                                                                     |__negative regulation of UDP-N-acetylglucosamine biosynthetic process 1 rec.
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Is a negative regulation of metabolic process
regulation of nucleobase-containing compound metabolic process
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Synonyms
  • "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT
    "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT
    "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT
    "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW
    "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED
    "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT
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