FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term tetrahydrofolylpolyglutamate biosynthetic process ID (Ontology) GO:0046901 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.
Also Known As "tetrahydrofolate polyglutamylation" ; "tetrahydrofolyl-[Glu](n) biosynthesis" ; "tetrahydrofolyl-[Glu](n) biosynthetic process" (for all, see Synonyms field below)
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       2
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Relevant FlyBase reports
 Genes
 tetrahydrofolylpolyglutamate biosynthetic process (all annotations which use CV term, excluding "NOT" statements)       2
     involved_in | tetrahydrofolylpolyglutamate biosynthetic process       2
Spanning Tree (Parents/Children)
Only view relationship: 
folic acid-containing compound metabolic process
 |__folic acid-containing compound biosynthetic process__
 |__tetrahydrofolylpolyglutamate metabolic process_______|
modified amino acid biosynthetic process                 |
 |__folic acid-containing compound biosynthetic process__|
pteridine-containing compound biosynthetic process       |
 |__folic acid-containing compound biosynthetic process__|
                                                         tetrahydrofolylpolyglutamate biosynthetic process  2 rec.
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Is a folic acid-containing compound biosynthetic process
tetrahydrofolylpolyglutamate metabolic process
Part of
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Synonyms
  • "folic acid-containing compound polyglutamylation" BROAD
    "tetrahydrofolate polyglutamylation" EXACT
    "tetrahydrofolyl-[Glu](n) biosynthesis" EXACT
    "tetrahydrofolyl-[Glu](n) biosynthetic process" EXACT
    "tetrahydrofolylpolyglutamate anabolism" EXACT
    "tetrahydrofolylpolyglutamate biosynthesis" EXACT
    "tetrahydrofolylpolyglutamate formation" EXACT
    "tetrahydrofolylpolyglutamate synthesis" EXACT
    "THF polyglutamylation" EXACT
Secondary IDs
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