FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term presynaptic active zone ID (Ontology) GO:0048786 (Gene Ontology)
Definition A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.[ PubMed:3152289 ]
Also Known As "pre-synaptic active zone" ; "presynaptic specialization"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      32
Genes (FBgn)  GO_CELLULAR_COMPONENT      28
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       2
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      11
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Insertions Constructs
 presynaptic active zone (all annotations which use CV term, excluding "NOT" statements)      33     40      2     12
     colocalizes_with | presynaptic active zone       --       2       --       --
     is_active_in | presynaptic active zone       --       6       --       --
     located_in | presynaptic active zone       --      24       --       --
     presynaptic active zone | adult stage      24       --       --      17
     presynaptic active zone | adult stage | decreased number       3       --       --       1
     presynaptic active zone | cell autonomous | larval stage | somatic clone       1       --       --       --
     presynaptic active zone | decreased number       3       --       --       --
     presynaptic active zone | decreased number | larval stage       7       --       --       1
     presynaptic active zone | decreased number | third instar larval stage      12       --       --      11
     presynaptic active zone | ectopic | pharate adult stage       2       --       --       2
     presynaptic active zone | increased number       3       --       --       --
     presynaptic active zone | increased number | larval stage       4       --       --       1
     presynaptic active zone | increased number | pupal stage       1       --       --       --
     presynaptic active zone | increased number | third instar larval stage       6       --       --       4
     presynaptic active zone | larval stage      42       --       --      26
     presynaptic active zone | somatic clone       2       --       --       --
     presynaptic active zone | third instar larval stage      51       --       --      23
Spanning Tree (Parents/Children)
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  cellular_component
   |__cellular anatomical structure
       |__presynaptic active zone  97 rec.
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Is a cellular anatomical structure
Part of presynapse
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Synonyms
  • "pre-synaptic active zone" EXACT
    "pre-synaptic active zone component" NARROW
    "presynaptic specialization" EXACT
Secondary IDs
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NIF_Subcellular:sao792027222