FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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General Information
Term dermatan sulfate proteoglycan biosynthetic process ID (Ontology) GO:0050651 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycans, which consist of a core protein linked to a dermatan sulfate glycosaminoglycan. The dermatan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-D-hexuronic acid-beta-(1,3)-N-acetyl-D-galactosamine. Tthe former can be a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter can be O-sulfated. Dermatan sulfate chains are covalently linked to serine/threonine residues (O-linked) of the core protein via a tetrasaccharide linker sequence (xylose-galactose-galactose-glucuronate).[ PubMed:17239763 ]
Also Known As "chondroitin sulfate B proteoglycan biosynthesis" ; "chondroitin sulfate B proteoglycan biosynthetic process" ; "dermatan sulfate proteoglycan anabolism" (for all, see Synonyms field below)
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proteoglycan metabolic process
 |__proteoglycan biosynthetic process________________
 |__dermatan sulfate proteoglycan metabolic process__|
protein O-linked glycosylation                       |
 |__protein O-linked glycosylation via xylose________|
glycoprotein biosynthetic process                    |
 |__proteoglycan biosynthetic process________________|
                                                     dermatan sulfate proteoglycan biosynthetic process  4 rec.
                                                      |__glycosaminoglycan-protein linkage region biosynthetic process 4 rec.
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Is a proteoglycan biosynthetic process
dermatan sulfate proteoglycan metabolic process
protein O-linked glycosylation via xylose
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Synonyms
  • "chondroitin sulfate B proteoglycan biosynthesis" EXACT
    "chondroitin sulfate B proteoglycan biosynthetic process" EXACT
    "dermatan sulfate proteoglycan anabolism" EXACT
    "dermatan sulfate proteoglycan biosynthesis" EXACT
    "dermatan sulfate proteoglycan formation" EXACT
    "dermatan sulfate proteoglycan synthesis" EXACT
    "dermatan sulphate proteoglycan biosynthesis" EXACT
    "dermatan sulphate proteoglycan biosynthetic process" EXACT
Secondary IDs
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MetaCyc:PWY-6568