FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term negative regulation of secretion ID (Ontology) GO:0051048 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
Also Known As "down regulation of secretion" ; "down-regulation of secretion" ; "downregulation of secretion"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 negative regulation of secretion (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | negative regulation of secretion       1
Spanning Tree (Parents/Children)
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negative regulation of biological process
 |__negative regulation of transport__
regulation of transport               |
 |__regulation of secretion___________|
 |__negative regulation of transport__|
                                      negative regulation of secretion  17 rec.
                                       |__negative regulation of bile acid secretion
                                       |__negative regulation of defecation
                                       |   |__negative regulation of defecation rhythm
                                       |__negative regulation of gamma-aminobutyric acid secretion
                                       |__negative regulation of gastric acid secretion
                                       |   |__negative regulation of gastrin-induced gastric acid secretion
                                       |__negative regulation of icosanoid secretion
                                       |   |__negative regulation of arachidonate secretion
                                       |   |__negative regulation of prostaglandin secretion
                                       |__negative regulation of lactation
                                       |__negative regulation of mucus secretion
                                       |__negative regulation of pancreatic juice secretion
                                       |__negative regulation of peptide secretion 7 rec.
                                       |   |__negative regulation of antimicrobial peptide secretion(+)
                                       |   |__negative regulation of peptide hormone secretion(+) 7 rec.
                                       |__negative regulation of renal sodium excretion
                                       |   |__negative regulation of renal sodium excretion by angiotensin
                                       |__negative regulation of saliva secretion
                                       |__negative regulation of secretion by cell 16 rec.
                                           |__negative regulation of aspartate secretion
                                           |__negative regulation of catecholamine secretion(+)
                                           |__negative regulation of exocytosis(+) 3 rec.
                                           |__negative regulation of extracellular matrix constituent secretion
                                           |__negative regulation of glutamate secretion(+) 1 rec.
                                           |__negative regulation of hormone secretion(+) 7 rec.
                                           |__negative regulation of neurotransmitter secretion(+) 3 rec.
                                           |__negative regulation of prostaglandin secretion
                                           |__negative regulation of protein secretion(+) 4 rec.
                                           |__negative regulation of serotonin secretion
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Is a regulation of secretion
negative regulation of transport
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Synonyms
  • "down regulation of secretion" EXACT
    "down-regulation of secretion" EXACT
    "downregulation of secretion" EXACT
    "inhibition of secretion" NARROW
Secondary IDs
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