FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term protein insertion into membrane ID (Ontology) GO:0051205 (Gene Ontology)
Definition The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.
Also Known As "integral membrane protein localization" ; "integral membrane protein positioning" ; "membrane protein localization" (for all, see Synonyms field below)
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cellular component organization
 |__membrane organization______________________________
macromolecule localization                             |
 |__intracellular protein localization_________________|
establishment of protein localization                  |
 |__establishment of protein localization to membrane__|
localization within membrane                           |
 |__establishment of protein localization to membrane__|
                                                       protein insertion into membrane  52 rec.
                                                        |__protein insertion into ER membrane 15 rec.
                                                        |   |__multi-pass transmembrane protein insertion into ER membrane
                                                        |   |__protein insertion into ER membrane by internal uncleaved signal-anchor sequence
                                                        |   |__protein insertion into ER membrane by N-terminal cleaved signal sequence
                                                        |   |__protein insertion into ER membrane by stop-transfer membrane-anchor sequence 1 rec.
                                                        |   |__tail-anchored membrane protein insertion into ER membrane 12 rec.
                                                        |__protein insertion into membrane raft
                                                        |   |__protein insertion into plasma membrane raft
                                                        |__protein insertion into mitochondrial membrane 37 rec.
                                                        |   |__protein insertion into mitochondrial inner membrane(+) 28 rec.
                                                        |   |__protein insertion into mitochondrial outer membrane(+) 8 rec.
                                                        |__protein insertion into plasma membrane
                                                            |__protein insertion into plasma membrane raft
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Is a establishment of protein localization to membrane
Part of intracellular protein localization
membrane organization
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Synonyms
  • "integral membrane protein localization" EXACT
    "integral membrane protein positioning" EXACT
    "membrane protein localization" EXACT
    "membrane protein positioning" EXACT
    "protein-membrane insertion" EXACT
Secondary IDs
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