FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term positive regulation of multicellular organismal process ID (Ontology) GO:0051240 (Gene Ontology)
Definition Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
Also Known As "up regulation of multicellular organismal process" ; "up-regulation of multicellular organismal process" ; "upregulation of multicellular organismal process"
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multicellular organismal process
 |__regulation of multicellular organismal process__
regulation of biological process                    |
 |__positive regulation of biological process_______|
 |__regulation of multicellular organismal process__|
                                                    positive regulation of multicellular organismal process  218 rec.
                                                     |__positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
                                                     |__positive regulation of adiponectin secretion
                                                     |__positive regulation of adipose tissue development
                                                     |__positive regulation of amyloid-beta clearance
                                                     |__positive regulation of animal organ morphogenesis
                                                     |   |__organ induction(+)
                                                     |   |__positive regulation of heart induction
                                                     |   |__positive regulation of nematode pharynx morphogenesis
                                                     |   |__positive regulation of odontogenesis(+)
                                                     |   |__positive regulation of otic vesicle morphogenesis
                                                     |   |__positive regulation of salivary gland formation by mesenchymal-epithelial signaling
                                                     |   |__positive regulation of ureteric bud formation
                                                     |   |__renal vesicle induction(+)
                                                     |__positive regulation of antipodal cell differentiation
                                                     |__positive regulation of apical ectodermal ridge formation
                                                     |__positive regulation of behavior 36 rec.
                                                     |   |__positive regulation of behavioral fear response
                                                     |   |__positive regulation of circadian sleep/wake cycle, sleep(+) 18 rec.
                                                     |   |__positive regulation of circadian sleep/wake cycle, wakefulness 5 rec.
                                                     |   |__positive regulation of egg-laying behavior
                                                     |   |__positive regulation of feeding behavior(+) 8 rec.
                                                     |   |__positive regulation of foraging behavior
                                                     |   |__positive regulation of host-seeking behavior
                                                     |   |__positive regulation of locomotion involved in locomotory behavior
                                                     |   |__positive regulation of locomotor rhythm 3 rec.
                                                     |   |__positive regulation of male mating behavior(+) 1 rec.
                                                     |   |__positive regulation of mechanosensory behavior 1 rec.
                                                     |__positive regulation of blood circulation 6 rec.
                                                     |   |__positive regulation of cerebral blood circulation
                                                     |   |__positive regulation of gastric mucosal blood circulation
                                                     |   |__positive regulation of heart contraction(+) 6 rec.
                                                     |__positive regulation of bone development
                                                     |__positive regulation of bone resorption
                                                     |__positive regulation of branching involved in lung morphogenesis
                                                     |   |__positive regulation of epithelial cell proliferation involved in lung bud dilation
                                                     |__positive regulation of branching involved in ureteric bud morphogenesis
                                                     |__positive regulation of branching morphogenesis of a nerve
                                                     |__positive regulation of cardiac endothelial to mesenchymal transition
                                                     |__positive regulation of cardiac ventricle development
                                                     |__positive regulation of cardiocyte differentiation 1 rec.
                                                     |   |__positive regulation of cardiac muscle cell differentiation(+) 1 rec.
                                                     |   |__positive regulation of cardiac vascular smooth muscle cell differentiation
                                                     |   |__positive regulation of cardioblast differentiation(+)
                                                     |   |__positive regulation of endocardial cushion cell differentiation
                                                     |__positive regulation of cartilage development
                                                     |   |__positive regulation of chondrocyte differentiation(+)
                                                     |__positive regulation of cell activation
                                                     |   |__positive regulation of astrocyte activation
                                                     |   |__positive regulation of endothelial cell activation
                                                     |   |__positive regulation of hepatic stellate cell activation
                                                     |   |__positive regulation of leukocyte activation(+)
                                                     |   |__positive regulation of platelet activation
                                                     |   |__positive regulation of satellite cell activation involved in skeletal muscle regeneration
                                                     |__positive regulation of chitin-based cuticle tanning
                                                     |   |__positive regulation of adult chitin-containing cuticle pigmentation
                                                     |__positive regulation of chylomicron remodeling
                                                     |__positive regulation of coagulation
                                                     |   |__positive regulation of blood coagulation(+)
                                                     |__positive regulation of cold-induced thermogenesis
                                                     |__positive regulation of collecting lymphatic vessel constriction
                                                     |__positive regulation of corticotropin secretion
                                                     |__positive regulation of cuticle pigmentation
                                                     |   |__positive regulation of adult chitin-containing cuticle pigmentation
                                                     |__positive regulation of cytokine production 3 rec.
                                                     |   |__positive regulation of amphiregulin production
                                                     |   |__positive regulation of chemokine production(+)
                                                     |   |__positive regulation of connective tissue growth factor production
                                                     |   |__positive regulation of cytokine production involved in immune response(+)
                                                     |   |__positive regulation of cytokine production involved in inflammatory response
                                                     |   |__positive regulation of endothelin production
                                                     |   |__positive regulation of fibroblast growth factor production
                                                     |   |__positive regulation of glial cell-derived neurotrophic factor production
                                                     |   |__positive regulation of granulocyte macrophage colony-stimulating factor production
                                                     |   |__positive regulation of hepatocyte growth factor production
                                                     |   |__positive regulation of interleukin-1 production(+)
                                                     |   |__positive regulation of interleukin-2 production
                                                     |   |__positive regulation of interleukin-3 production
                                                     |   |__positive regulation of interleukin-4 production
                                                     |   |__positive regulation of interleukin-5 production
                                                     |   |__positive regulation of interleukin-6 production
                                                     |   |__positive regulation of interleukin-7 production
                                                     |   |__positive regulation of interleukin-8 production
                                                     |   |__positive regulation of interleukin-9 production
                                                     |   |__positive regulation of interleukin-10 production
                                                     |   |__positive regulation of interleukin-11 production
                                                     |   |__positive regulation of interleukin-12 production
                                                     |   |__positive regulation of interleukin-13 production
                                                     |   |__positive regulation of interleukin-15 production
                                                     |   |__positive regulation of interleukin-16 production
                                                     |   |__positive regulation of interleukin-17 production(+)
                                                     |   |__positive regulation of interleukin-18 production
                                                     |   |__positive regulation of interleukin-19 production
                                                     |   |__positive regulation of interleukin-20 production
                                                     |   |__positive regulation of interleukin-21 production
                                                     |   |__positive regulation of interleukin-22 production
                                                     |   |__positive regulation of interleukin-23 production
                                                     |   |__positive regulation of interleukin-24 production
                                                     |   |__positive regulation of interleukin-25 production
                                                     |   |__positive regulation of interleukin-26 production
                                                     |   |__positive regulation of interleukin-27 production
                                                     |   |__positive regulation of interleukin-32 production
                                                     |   |__positive regulation of interleukin-33 production
                                                     |   |__positive regulation of interleukin-34 production
                                                     |   |__positive regulation of interleukin-35 production
                                                     |   |__positive regulation of interleukin-37 production
                                                     |   |__positive regulation of macrophage colony-stimulating factor production(+)
                                                     |   |__positive regulation of platelet-derived growth factor production
                                                     |   |__positive regulation of transforming growth factor beta production(+)
                                                     |   |__positive regulation of tumor necrosis factor superfamily cytokine production(+)
                                                     |   |__positive regulation of type I interferon production(+) 2 rec.
                                                     |   |__positive regulation of type II interferon production
                                                     |   |__positive regulation of type III interferon production
                                                     |   |__positive regulation of vascular endothelial growth factor production 1 rec.
                                                     |__positive regulation of determination of dorsal identity 1 rec.
                                                     |__positive regulation of digestive system process 1 rec.
                                                     |   |__positive regulation of defecation(+)
                                                     |   |__positive regulation of gastric acid secretion(+)
                                                     |   |__positive regulation of gastric emptying
                                                     |   |__positive regulation of hindgut contraction 1 rec.
                                                     |   |__positive regulation of intestinal absorption(+)
                                                     |   |__positive regulation of intestinal epithelial structure maintenance
                                                     |   |__positive regulation of pancreatic juice secretion
                                                     |   |__positive regulation of saliva secretion
                                                     |   |__positive regulation of small intestinal transit
                                                     |__positive regulation of eclosion 3 rec.
                                                     |__positive regulation of embryo sac central cell differentiation
                                                     |__positive regulation of embryo sac egg cell differentiation
                                                     |__positive regulation of embryonic development 3 rec.
                                                     |   |__positive regulation of dermatome development
                                                     |   |__positive regulation of gastrulation 1 rec.
                                                     |__positive regulation of embryonic pattern specification
                                                     |__positive regulation of endothelial tube morphogenesis
                                                     |__positive regulation of epidermal growth factor receptor signaling pathway involved in heart process
                                                     |__positive regulation of epithelial cell-cell adhesion involved in epithelium migration 1 rec.
                                                     |__positive regulation of epithelial to mesenchymal transition
                                                     |   |__positive regulation of cardiac epithelial to mesenchymal transition(+)
                                                     |   |__positive regulation of mesodermal to mesenchymal transition involved in gastrulation
                                                     |   |__positive regulation of neural crest formation(+)
                                                     |__positive regulation of epithelial tube formation
                                                     |   |__pancreas induction
                                                     |   |__positive regulation of ureteric bud formation
                                                     |__positive regulation of fear response
                                                     |   |__positive regulation of behavioral fear response
                                                     |__positive regulation of female pigmentation 1 rec.
                                                     |__positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
                                                     |__positive regulation of germ cell proliferation 1 rec.
                                                     |   |__positive regulation of male germ cell proliferation
                                                     |__positive regulation of glomerular filtration
                                                     |__positive regulation of gonad development 1 rec.
                                                     |   |__positive regulation of female gonad development(+)
                                                     |   |__positive regulation of male gonad development 1 rec.
                                                     |__positive regulation of gonadotropin secretion
                                                     |   |__positive regulation of follicle-stimulating hormone secretion
                                                     |   |__positive regulation of luteinizing hormone secretion
                                                     |__positive regulation of hair cycle
                                                     |__positive regulation of hair follicle development
                                                     |   |__positive regulation of hair follicle maturation(+)
                                                     |__positive regulation of heat dissipation
                                                     |__positive regulation of heat generation
                                                     |   |__positive regulation of fever generation(+)
                                                     |__positive regulation of hemopoiesis
                                                     |   |__positive regulation of leukocyte differentiation(+)
                                                     |__positive regulation of hepatocyte differentiation
                                                     |__positive regulation of high-density lipoprotein particle assembly
                                                     |__positive regulation of histamine secretion by mast cell
                                                     |__positive regulation of imaginal disc-derived wing vein specification
                                                     |__positive regulation of intestinal epithelial cell development
                                                     |__positive regulation of keratinocyte differentiation
                                                     |__positive regulation of kidney development
                                                     |   |__positive regulation of glomerulus development(+)
                                                     |   |__positive regulation of mesonephros development(+)
                                                     |   |__positive regulation of metanephric cap mesenchymal cell proliferation
                                                     |   |__positive regulation of metanephros development(+)
                                                     |   |__renal vesicle induction(+)
                                                     |__positive regulation of lactation
                                                     |   |__positive regulation of lactation by mesenchymal-epithelial cell signaling
                                                     |__positive regulation of leaf development
                                                     |   |__positive regulation of leaflet formation by auxin mediated signaling pathway
                                                     |__positive regulation of lens fiber cell differentiation
                                                     |__positive regulation of leukotriene production involved in inflammatory response
                                                     |__positive regulation of lipoprotein particle clearance
                                                     |   |__positive regulation of chylomicron remnant clearance
                                                     |   |__positive regulation of high-density lipoprotein particle clearance
                                                     |   |__positive regulation of low-density lipoprotein particle clearance
                                                     |   |__positive regulation of very-low-density lipoprotein particle clearance
                                                     |__positive regulation of lung alveolus development
                                                     |__positive regulation of lung ciliated cell differentiation
                                                     |__positive regulation of lung goblet cell differentiation
                                                     |__positive regulation of male germ-line stem cell asymmetric division
                                                     |__positive regulation of male pigmentation
                                                     |__positive regulation of mammary gland epithelial cell proliferation
                                                     |__positive regulation of mammary placode formation by mesenchymal-epithelial signaling
                                                     |__positive regulation of mammary stem cell proliferation
                                                     |__positive regulation of maternal process involved in parturition
                                                     |__positive regulation of mesenchymal cell proliferation involved in lung development
                                                     |__positive regulation of mucus secretion
                                                     |__positive regulation of multicellular organism growth 28 rec.
                                                     |__positive regulation of muscle adaptation
                                                     |   |__positive regulation of cardiac muscle adaptation(+)
                                                     |   |__positive regulation of muscle atrophy
                                                     |   |__positive regulation of muscle hyperplasia
                                                     |   |__positive regulation of skeletal muscle hypertrophy
                                                     |   |__positive regulation of smooth muscle hypertrophy
                                                     |__positive regulation of muscle contraction 2 rec.
                                                     |   |__positive regulation of smooth muscle contraction(+) 2 rec.
                                                     |   |__positive regulation of striated muscle contraction(+)
                                                     |__positive regulation of muscle hypertrophy
                                                     |   |__positive regulation of cardiac muscle hypertrophy(+)
                                                     |   |__positive regulation of skeletal muscle hypertrophy
                                                     |   |__positive regulation of smooth muscle hypertrophy
                                                     |__positive regulation of muscle organ development 6 rec.
                                                     |   |__positive regulation of somitomeric trunk muscle development
                                                     |   |__positive regulation of striated muscle tissue development(+)
                                                     |__positive regulation of nematode male tail tip morphogenesis
                                                     |__positive regulation of nervous system development 116 rec.
                                                     |   |__positive regulation of neurogenesis(+) 72 rec.
                                                     |   |__positive regulation of synapse assembly(+) 48 rec.
                                                     |__positive regulation of nervous system process 5 rec.
                                                     |   |__positive regulation of detection of mechanical stimulus involved in sensory perception of touch
                                                     |   |__positive regulation of inhibitory postsynaptic potential
                                                     |   |__positive regulation of myelination
                                                     |   |__positive regulation of sensory perception of bitter taste
                                                     |   |__positive regulation of sensory perception of pain 3 rec.
                                                     |   |__positive regulation of sensory perception of sweet taste
                                                     |   |__positive regulation of transmission of nerve impulse(+) 2 rec.
                                                     |__positive regulation of neural crest cell differentiation
                                                     |   |__positive regulation of neural crest cell fate specification
                                                     |__positive regulation of neurotrophin production
                                                     |__positive regulation of oogenesis 2 rec.
                                                     |__positive regulation of organ growth 13 rec.
                                                     |   |__positive regulation of heart growth(+)
                                                     |__positive regulation of ossification
                                                     |   |__positive regulation of bone mineralization(+)
                                                     |__positive regulation of ovulation 2 rec.
                                                     |__positive regulation of pancreatic A cell differentiation
                                                     |__positive regulation of parathyroid hormone secretion
                                                     |__positive regulation of penile erection
                                                     |__positive regulation of photoreceptor cell differentiation 9 rec.
                                                     |   |__positive regulation of compound eye photoreceptor cell differentiation(+) 3 rec.
                                                     |   |__positive regulation of eye photoreceptor cell development(+) 2 rec.
                                                     |   |__positive regulation of retinal rod cell fate commitment
                                                     |__positive regulation of plant organ morphogenesis
                                                     |__positive regulation of post-embryonic development
                                                     |   |__positive regulation of flower development
                                                     |   |__positive regulation of lateral root development
                                                     |   |__positive regulation of long-day photoperiodism, flowering
                                                     |   |__positive regulation of nematode larval development(+)
                                                     |   |__positive regulation of photomorphogenesis
                                                     |   |__positive regulation of seed germination
                                                     |   |__positive regulation of short-day photoperiodism, flowering
                                                     |   |__positive regulation of stomatal complex development
                                                     |   |__positive regulation of thermomorphogenesis
                                                     |__positive regulation of pupariation
                                                     |__positive regulation of relaxation of muscle
                                                     |   |__positive regulation of relaxation of cardiac muscle
                                                     |   |__positive regulation of relaxation of smooth muscle(+)
                                                     |__positive regulation of renal albumin absorption
                                                     |__positive regulation of renal amino acid absorption
                                                     |__positive regulation of renal phosphate excretion
                                                     |__positive regulation of renal sodium excretion
                                                     |   |__positive regulation of renal sodium excretion by pressure natriuresis
                                                     |__positive regulation of renal water transport
                                                     |__positive regulation of respiratory burst involved in inflammatory response
                                                     |__positive regulation of respiratory gaseous exchange
                                                     |__positive regulation of retina development in camera-type eye
                                                     |   |__positive regulation of neural retina development
                                                     |__positive regulation of salivary gland boundary specification
                                                     |   |__positive regulation of adult salivary gland boundary specification
                                                     |   |__positive regulation of larval salivary gland boundary specification
                                                     |__positive regulation of seed dormancy process
                                                     |__positive regulation of seed maturation
                                                     |__positive regulation of sperm capacitation
                                                     |__positive regulation of spore-bearing organ development
                                                     |   |__positive regulation of aecium development
                                                     |   |__positive regulation of ascus development
                                                     |   |__positive regulation of basidium development
                                                     |   |__positive regulation of conidiophore development(+)
                                                     |   |__positive regulation of oogonium development
                                                     |   |__positive regulation of sorocarp stalk cell differentiation
                                                     |   |__positive regulation of sporangium development(+)
                                                     |   |__positive regulation of sporocarp development involved in sexual reproduction(+)
                                                     |   |__positive regulation of telium development
                                                     |   |__positive regulation of uredinium development
                                                     |   |__positive regulation of zygosporangium development
                                                     |__positive regulation of stem cell population maintenance
                                                     |   |__positive regulation of somatic stem cell population maintenance(+)
                                                     |__positive regulation of steroid hormone secretion 1 rec.
                                                     |   |__positive regulation of androgen secretion
                                                     |   |__positive regulation of corticosteroid hormone secretion(+)
                                                     |   |__positive regulation of ecdysteroid secretion 1 rec.
                                                     |   |__positive regulation of estradiol secretion
                                                     |   |__positive regulation of estrogen secretion
                                                     |   |__positive regulation of estrone secretion
                                                     |   |__positive regulation of progesterone secretion
                                                     |__positive regulation of synergid differentiation
                                                     |__positive regulation of thyroid gland epithelial cell proliferation
                                                     |__positive regulation of tissue remodeling
                                                     |   |__positive regulation of blood vessel remodeling(+)
                                                     |   |__positive regulation of bone remodeling
                                                     |   |__positive regulation of connective tissue replacement(+)
                                                     |   |__positive regulation of erythrocyte clearance
                                                     |   |__positive regulation of mammary gland involution
                                                     |__positive regulation of tolerance induction
                                                     |   |__positive regulation of B cell tolerance induction(+)
                                                     |   |__positive regulation of central tolerance induction(+)
                                                     |   |__positive regulation of lymphocyte anergy(+)
                                                     |   |__positive regulation of macrophage tolerance induction
                                                     |   |__positive regulation of natural killer cell tolerance induction
                                                     |   |__positive regulation of T cell tolerance induction(+)
                                                     |   |__positive regulation of tolerance induction dependent upon immune response(+)
                                                     |   |__positive regulation of tolerance induction to self antigen
                                                     |__positive regulation of transcytosis 1 rec.
                                                     |__positive regulation of transport across blood-brain barrier
                                                     |   |__positive regulation of lipid transport across blood-brain barrier
                                                     |__positive regulation of trophoblast cell migration
                                                     |__positive regulation of type B pancreatic cell development
                                                     |__positive regulation of ureter smooth muscle cell differentiation
                                                     |__positive regulation of vasculature development
                                                     |   |__positive regulation of angiogenesis(+)
                                                     |__positive regulation of vasoconstriction
                                                     |   |__positive regulation of vascular associated smooth muscle contraction(+)
                                                     |__positive regulation of very-low-density lipoprotein particle remodeling
                                                     |__positive regulation of vitellogenesis
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Is a positive regulation of biological process
regulation of multicellular organismal process
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Synonyms
  • "activation of multicellular organismal process" NARROW
    "stimulation of multicellular organismal process" NARROW
    "up regulation of multicellular organismal process" EXACT
    "up-regulation of multicellular organismal process" EXACT
    "upregulation of multicellular organismal process" EXACT
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