FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term negative regulation of hydrolase activity ID (Ontology) GO:0051346 (Gene Ontology)
Definition Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
Also Known As "down regulation of hydrolase activity" ; "down-regulation of hydrolase activity" ; "downregulation of hydrolase activity" (for all, see Synonyms field below)
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negative regulation of molecular function
 |__negative regulation of catalytic activity__
regulation of catalytic activity               |
 |__negative regulation of catalytic activity__|
 |__regulation of hydrolase activity___________|
                                               negative regulation of hydrolase activity
                                                |__negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
                                                |__negative regulation of beta-galactosidase activity
                                                |__negative regulation of cyclic-nucleotide phosphodiesterase activity
                                                |__negative regulation of GTPase activity
                                                |__negative regulation of lipase activity
                                                |   |__negative regulation of lipoprotein lipase activity
                                                |__negative regulation of peptidase activity
                                                |   |__negative regulation of endopeptidase activity(+)
                                                |   |__negative regulation of metallopeptidase activity
                                                |   |__negative regulation of serine-type peptidase activity(+)
                                                |__negative regulation of phosphatase activity
                                                    |__negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
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Is a negative regulation of catalytic activity
regulation of hydrolase activity
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Synonyms
  • "down regulation of hydrolase activity" EXACT
    "down-regulation of hydrolase activity" EXACT
    "downregulation of hydrolase activity" EXACT
    "hydrolase inhibitor" EXACT
    "inhibition of hydrolase activity" NARROW
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