FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction ID (Ontology) GO:0051897 (Gene Ontology)
Definition Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction.
Also Known As "positive regulation of phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction" ; "positive regulation of PI3K-PKB/Akt pathway" ; "positive regulation of PI3K/Akt signal transduction" (for all, see Synonyms field below)
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      17
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (all annotations which use CV term, excluding "NOT" statements)      17
     involved_in | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction      17
Spanning Tree (Parents/Children)
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positive regulation of signal transduction
 |__positive regulation of intracellular signal transduction__________________________
phosphatidylinositol 3-kinase/protein kinase B signal transduction                    |
 |__regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction__|
regulation of intracellular signal transduction                                       |
 |__regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction__|
 |__positive regulation of intracellular signal transduction__________________________|
                                                                                      positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  17 rec.
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Is a regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
positive regulation of intracellular signal transduction
Part of
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Synonyms
  • "activation of protein kinase B signaling cascade" NARROW
    "positive regulation of AKT signaling cascade" RELATED
    "positive regulation of AKT signalling cascade" RELATED
    "positive regulation of phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction" EXACT
    "positive regulation of PI3K-PKB/Akt pathway" EXACT
    "positive regulation of PI3K/Akt signal transduction" EXACT
    "positive regulation of PI3K/PKB signal transduction" EXACT
    "positive regulation of PKB signaling cascade" RELATED
    "positive regulation of PKB signalling cascade" RELATED
    "positive regulation of protein kinase B signaling" RELATED
    "positive regulation of protein kinase B signaling cascade" RELATED
    "positive regulation of protein kinase B signalling cascade" RELATED
    "stimulation of protein kinase B signaling cascade" NARROW
    "up regulation of protein kinase B signaling cascade" RELATED
    "up-regulation of protein kinase B signaling cascade" RELATED
    "upregulation of protein kinase B signaling cascade" RELATED
Secondary IDs
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Reactome:R-HSA-1257604 "PIP3 activates AKT signaling"
Reactome:R-HSA-165158 "Activation of AKT2"
Reactome:R-HSA-9027276 "Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"
Reactome:R-HSA-9028335 "Activated NTRK2 signals through PI3K"
Reactome:R-HSA-9603381 "Activated NTRK3 signals through PI3K"