FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term symbiont-mediated suppression of host signal transduction pathway ID (Ontology) GO:0052029 (Gene Ontology)
Definition A process in which a symbiont interferes with, inhibits or disrupts a host signal transduction pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Also Known As "disruption by symbiont of host signal transduction pathway" ; "disruption of host signal transduction pathway" ; "down regulation by symbiont of host signal transduction pathway" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
No relevant records available
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
Spanning Tree (Parents/Children)
Only view relationship: 
  symbiont-mediated perturbation of host cellular process
   |__symbiont-mediated perturbation of host signal transduction pathway
       |__symbiont-mediated suppression of host signal transduction pathway
           |__effector-mediated suppression of host salicylic acid-mediated innate immune signaling
           |__symbiont-mediated suppression of host calcium-mediated signal transduction
           |__symbiont-mediated suppression of host cAMP/PKA signal transduction
           |__symbiont-mediated suppression of host G protein-coupled receptor signal transduction
           |   |__symbiont-mediated suppression of host chemokine signal transduction pathway
           |__symbiont-mediated suppression of host interferon-mediated signaling pathway
           |   |__symbiont-mediated suppression of host type I interferon-mediated signaling pathway
           |   |__symbiont-mediated suppression of host type II interferon-mediated signaling pathway
           |   |__symbiont-mediated suppression of host type III interferon-mediated signaling pathway
           |__symbiont-mediated suppression of host JAK-STAT cascade
           |   |__symbiont-mediated suppression of host JAK-STAT cascade via inhibition of host IRF9 activity
           |   |__symbiont-mediated suppression of host JAK-STAT cascade via inhibition of host TYK2 activity
           |   |__symbiont-mediated suppression of host JAK-STAT cascade via inhibition of JAK1 activity
           |   |__symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT activity(+)
           |__symbiont-mediated suppression of host MAPK cascade
           |__symbiont-mediated suppression of host NF-kappaB cascade
           |__symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway
           |   |__symbiont-mediated suppression of cytoplasmic pattern recognition receptor signaling pathway(+)
           |__symbiont-mediated suppression of host PKR/eIFalpha signaling
           |__symbiont-mediated suppression of host signal transduction pathway via antagonism of host cell surface receptor
           |__symbiont-mediated suppression of host toll-like receptor signaling pathway
           |__symbiont-mediated suppression of host TRAF-mediated signal transduction
           |__symbiont-mediated suppression of host tumor necrosis factor-mediated signaling pathway
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a symbiont-mediated perturbation of host signal transduction pathway
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "disruption by symbiont of host signal transduction pathway" EXACT
    "disruption of host signal transduction pathway" EXACT
    "down regulation by symbiont of host signal transduction pathway" EXACT
    "down-regulation by symbiont of host signal transduction pathway" EXACT
    "downregulation by symbiont of host signal transduction pathway" EXACT
    "inhibition by symbiont of host signal transduction pathway" NARROW
    "negative modulation by organism of host signal transduction pathway" EXACT
    "negative regulation by organism of signal transduction in other organism involved in symbiotic interaction" BROAD
    "negative regulation by symbiont of host signal transduction pathway" EXACT
    "suppression by symbiont of host signal transduction pathway" EXACT
Secondary IDs
hide External Crossreferences & Linkouts