FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term symbiont-mediated suppression of host immune response ID (Ontology) GO:0052562 (Gene Ontology)
Definition A process in which a symbiont interferes with, inhibits or disrupts the normal execution of an immune response of the host organism. The immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Also Known As "down regulation by symbiont of host immune response" ; "down-regulation by symbiont of host immune response" ; "downregulation by symbiont of host immune response" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
No relevant records available
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
Spanning Tree (Parents/Children)
Only view relationship: 
  symbiont-mediated perturbation of host defense response
   |__symbiont-mediated perturbation of host immune response
       |__symbiont-mediated suppression of host immune response
           |__symbiont-mediated suppression of host adaptive immune response
           |   |__symbiont-mediated suppression of host antigen processing and presentation(+)
           |   |__symbiont-mediated suppression of host B-cell mediated immune response
           |   |__symbiont-mediated suppression of host T-cell mediated immune response
           |__symbiont-mediated suppression of host immunoglobulin-mediated immune response
           |__symbiont-mediated suppression of host innate immune response
               |__effector-mediated suppression of host innate immune response(+)
               |__symbiont-mediated suppression of host complement activation(+)
               |__symbiont-mediated suppression of host ISG15-protein conjugation
               |__symbiont-mediated suppression of host JAK-STAT cascade via inhibition of host IRF9 activity
               |__symbiont-mediated suppression of host JAK-STAT cascade via inhibition of host TYK2 activity
               |__symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway(+)
               |__symbiont-mediated suppression of host RNAi-mediated antiviral immune response
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a symbiont-mediated perturbation of host immune response
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "down regulation by symbiont of host immune response" EXACT
    "down-regulation by symbiont of host immune response" EXACT
    "downregulation by symbiont of host immune response" EXACT
    "inhibition by symbiont of host immune response" NARROW
    "negative regulation by organism of immune response of other organism involved in symbiotic interaction" BROAD
    "negative regulation by symbiont of host immune response" EXACT
    "suppression by symbiont of host immune response" EXACT
Secondary IDs
hide External Crossreferences & Linkouts