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General Information
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| Term |
coenzyme F420-dependent bicyclic nitroimidazole catabolic process |
ID (Ontology) |
GO:0052799 (Gene Ontology) |
| Definition |
The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. Hydride, from reduced coenzyme F420, is added to the bicyclic nitroimidazole, resulting in unstable substances that break down to form three stable products. The elimination of nitrous acid produces the corresponding des-nitroimidazole; hydrolysis produces a related compound; and further reduction creates an aromatic hydroxylamine metabolite that degrades further. These reactions release hyponitrous acid and nitrous acid, which is unstable and disproportionates into nitric oxide (NO) and other reactive nitrogen intermediates.[ PubMed:16387854 PubMed:19039139 ] |
| Also Known As |
"coenzyme F420-dependent nitroimidazole breakdown" ; "coenzyme F420-dependent nitroimidazole catabolism" ; "coenzyme F420-dependent nitroimidazole reduction" |
| Comment |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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No relevant records available
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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No relevant statements available
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Relationships
