FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing ID (Ontology) GO:0055052 (Gene Ontology)
Definition A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.
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ATPase dependent transmembrane transport complex__
plasma membrane protein complex___________________|
                                                  ATP-binding cassette (ABC) transporter complex
                                                   |__ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
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