FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term Sertoli cell differentiation ID (Ontology) GO:0060008 (Gene Ontology)
Definition The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.
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gonad development
 |__male gonad development__________________________
reproductive process                                |
 |__developmental process involved in reproduction__|
cell differentiation                                |
 |__epithelial cell differentiation_________________|
developmental process                               |
 |__developmental process involved in reproduction__|
development of primary male sexual characteristics  |
 |__male gonad development__________________________|
epithelium development                              |
 |__epithelial cell differentiation_________________|
                                                    Sertoli cell differentiation
                                                     |__Sertoli cell development
                                                     |   |__establishment of Sertoli cell barrier(+)
                                                     |__Sertoli cell fate commitment
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Is a developmental process involved in reproduction
epithelial cell differentiation
Part of male gonad development
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