General Information
Term	relaxation of vascular associated smooth muscle	ID (Ontology)	GO:0060087 (Gene Ontology)
Definition	A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.[ PubMed:15867178 PubMed:19996365 PubMed:27389411 ]
Also Known As	"relaxation of vascular smooth muscle" ; "vascular smooth muscle relaxation"
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Records annotated with this exact term (annotations to child terms are NOT included)
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General Information

Term

relaxation of vascular associated smooth muscle

ID (Ontology)

GO:0060087 (Gene Ontology)

Definition

A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.[ PubMed:15867178 PubMed:19996365 PubMed:27389411 ]

Also Known As

"relaxation of vascular smooth muscle" ; "vascular smooth muscle relaxation"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

regulation of smooth muscle contraction
 |__negative regulation of smooth muscle contraction__
negative regulation of muscle contraction             |
 |__negative regulation of smooth muscle contraction__|
relaxation of muscle                                  |
 |__relaxation of smooth muscle_______________________|
blood vessel diameter maintenance                     |
 |__vasodilation______________________________________|
                                                      relaxation of vascular associated smooth muscle

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Is a	relaxation of smooth muscle negative regulation of smooth muscle contraction
Part of	vasodilation
Synonyms & Secondary IDs
Synonyms
	"negative regulation of relaxation of vascular smooth muscle" RELATED "positive regulation of relaxation of vascular smooth muscle" RELATED "regulation of relaxation of vascular smooth muscle" RELATED "relaxation of vascular smooth muscle" EXACT "vascular smooth muscle relaxation" EXACT
Secondary IDs

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Is a

relaxation of smooth muscle
negative regulation of smooth muscle contraction

Part of

vasodilation

Synonyms & Secondary IDs

Synonyms

"negative regulation of relaxation of vascular smooth muscle" RELATED
"positive regulation of relaxation of vascular smooth muscle" RELATED
"regulation of relaxation of vascular smooth muscle" RELATED
"relaxation of vascular smooth muscle" EXACT
"vascular smooth muscle relaxation" EXACT

Secondary IDs

External Crossreferences & Linkouts