FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term negative regulation of ryanodine-sensitive calcium-release channel activity ID (Ontology) GO:0060315 (Gene Ontology)
Definition Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.
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regulation of transmembrane transporter activity
 |__regulation of ryanodine-sensitive calcium-release channel activity______
negative regulation of ion transmembrane transporter activity               |
 |__negative regulation of calcium ion transmembrane transporter activity___|
regulation of release of sequestered calcium ion into cytosol               |
 |__negative regulation of release of sequestered calcium ion into cytosol__|
 |__regulation of ryanodine-sensitive calcium-release channel activity______|
positive regulation of sequestering of calcium ion                          |
 |__negative regulation of release of sequestered calcium ion into cytosol__|
negative regulation of calcium ion transmembrane transport                  |
 |__negative regulation of release of sequestered calcium ion into cytosol__|
 |__negative regulation of calcium ion transmembrane transporter activity___|
                                                                            negative regulation of ryanodine-sensitive calcium-release channel activity
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Is a negative regulation of release of sequestered calcium ion into cytosol
regulation of ryanodine-sensitive calcium-release channel activity
negative regulation of calcium ion transmembrane transporter activity
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