FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term establishment of blood-brain barrier ID (Ontology) GO:0060856 (Gene Ontology)
Definition Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.[ PubMed:20080302 PubMed:30280653 ]
Also Known As "establishment of BBB" ; "establishment of blood/brain barrier"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       2
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 Genes
 establishment of blood-brain barrier (all annotations which use CV term, excluding "NOT" statements)       2
     involved_in | establishment of blood-brain barrier       2
Spanning Tree (Parents/Children)
Only view relationship: 
nervous system development
 |__central nervous system development__
cell differentiation                    |
 |__cell development____________________|
system development                      |
 |__central nervous system development__|
anatomical structure development        |
 |__cell development____________________|
cellular developmental process          |
 |__cell development____________________|
                                        establishment of blood-brain barrier  23 rec.
                                         |__establishment of endothelial blood-brain barrier
                                         |__establishment of glial blood-brain barrier 17 rec.
                                         |__regulation of establishment of blood-brain barrier 4 rec.
                                             |__negative regulation of establishment of blood-brain barrier 1 rec.
                                             |__positive regulation of establishment of blood-brain barrier
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Is a cell development
Part of central nervous system development
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Synonyms
  • "establishment of BBB" EXACT
    "establishment of blood/brain barrier" EXACT
Secondary IDs
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