FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term cardiac conduction ID (Ontology) GO:0061337 (Gene Ontology)
Definition Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.
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heart contraction________________
regulation of blood circulation__|
                                 regulation of heart contraction
                                  |__cardiac conduction
                                      |__cell communication involved in cardiac conduction
                                      |   |__atrial cardiac muscle cell to AV node cell communication(+)
                                      |   |__AV node cell to bundle of His cell communication(+)
                                      |   |__bundle of His cell to Purkinje myocyte communication(+)
                                      |   |__cell communication by electrical coupling involved in cardiac conduction(+)
                                      |   |__cell-cell signaling involved in cardiac conduction(+)
                                      |   |__Purkinje myocyte to ventricular cardiac muscle cell communication(+)
                                      |   |__SA node cell to atrial cardiac muscle cell communication(+)
                                      |__regulation of cardiac conduction
                                      |   |__negative regulation of cardiac conduction
                                      |   |__positive regulation of cardiac conduction
                                      |   |__regulation of atrial cardiac muscle cell action potential(+)
                                      |__regulation of heart rate by cardiac conduction
                                      |__regulation of the force of heart contraction by cardiac conduction
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Is a regulation of heart contraction
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Reactome:R-HSA-5576891 "Cardiac conduction"