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| Term | chaperone-mediated autophagy | ID (Ontology) | GO:0061684 (Gene Ontology) |
| Definition | The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.[ PubMed:22743996 PubMed:23434281 ] | ||
| Also Known As | "chaperone-assisted selective autophagy" | ||
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catabolic process |__autophagy___________________________ macromolecule catabolic process | |__protein catabolic process___________| protein metabolic process | |__protein catabolic process___________| process utilizing autophagic mechanism | |__autophagy___________________________| chaperone-mediated autophagy |__chaperone-mediated autophagy translocation complex assembly |__protein targeting to lysosome involved in chaperone-mediated autophagy |__regulation of chaperone-mediated autophagy |__negative regulation of chaperone-mediated autophagy |__positive regulation of chaperone-mediated autophagy |
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autophagy protein catabolic process |
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External Crossreferences & Linkouts
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Reactome:R-HSA-9613829 "Chaperone Mediated Autophagy" Wikipedia:Chaperone-mediated_autophagy |
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