General Information
Term	Tapasin-ERp57 complex	ID (Ontology)	GO:0061779 (Gene Ontology)
Definition	Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role.[ PubMed:17603487 ]
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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General Information

Term

Tapasin-ERp57 complex

ID (Ontology)

GO:0061779 (Gene Ontology)

Definition

Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role.[ PubMed:17603487 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

endoplasmic reticulum
 |__endoplasmic reticulum protein-containing complex__
endoplasmic reticulum membrane                        |
 |__MHC class I peptide loading complex_______________|
membrane                                              |
 |__membrane protein complex__________________________|
protein-containing complex                            |
 |__membrane protein complex__________________________|
 |__endoplasmic reticulum protein-containing complex__|
membrane protein complex                              |
 |__MHC class I peptide loading complex_______________|
endoplasmic reticulum protein-containing complex      |
 |__MHC class I peptide loading complex_______________|
                                                      Tapasin-ERp57 complex

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Relationships
Is a	membrane protein complex endoplasmic reticulum protein-containing complex
Part of	MHC class I peptide loading complex
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts

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Is a

membrane protein complex
endoplasmic reticulum protein-containing complex

Part of

MHC class I peptide loading complex

Synonyms & Secondary IDs

Synonyms

Secondary IDs

External Crossreferences & Linkouts