Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
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| Term | Tapasin-ERp57 complex | ID (Ontology) | GO:0061779 (Gene Ontology) |
| Definition | Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role.[ PubMed:17603487 ] | ||
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protein-containing complex |__membrane protein complex__________________________ |__endoplasmic reticulum protein-containing complex__| Tapasin-ERp57 complex |
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membrane protein complex endoplasmic reticulum protein-containing complex |
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| Part of | MHC class I peptide loading complex | ||
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