FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term autophagosome-lysosome fusion ID (Ontology) GO:0061909 (Gene Ontology)
Definition The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.[ PubMed:28077293 ]
Also Known As "autophagosome-vacuole fusion"
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  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      10
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 autophagosome-lysosome fusion (all annotations which use CV term, excluding "NOT" statements)      10
     acts_upstream_of_positive_effect | autophagosome-lysosome fusion       1
     involved_in | autophagosome-lysosome fusion      10
Spanning Tree (Parents/Children)
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autophagy
 |__macroautophagy__________
vesicle organization        |
 |__vesicle fusion__________|
vesicle-mediated transport  |
 |__vesicle fusion__________|
organelle membrane fusion   |
 |__vesicle fusion__________|
                            autophagosome-lysosome fusion  10 rec.
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Is a vesicle fusion
Part of macroautophagy
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Synonyms
  • "autophagosome fusion" BROAD
    "autophagosome-vacuole fusion" EXACT
Secondary IDs
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