FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term negative regulation of small molecule metabolic process ID (Ontology) GO:0062014 (Gene Ontology)
Definition Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.
Also Known As "negative regulation of small molecule metabolism"
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regulation of metabolic process
 |__negative regulation of metabolic process________
 |__regulation of small molecule metabolic process__|
negative regulation of cellular process             |
 |__negative regulation of metabolic process________|
                                                    negative regulation of small molecule metabolic process  4 rec.
                                                     |__negative regulation of (R)-mevalonic acid biosynthetic process
                                                     |__negative regulation of acetate catabolic process
                                                     |__negative regulation of aflatoxin biosynthetic process
                                                     |__negative regulation of alcohol biosynthetic process
                                                     |   |__negative regulation of abscisic acid biosynthetic process
                                                     |   |__negative regulation of aldosterone biosynthetic process
                                                     |   |__negative regulation of asperfuranone biosynthetic process
                                                     |   |__negative regulation of butyryl-CoA catabolic process to butanol
                                                     |   |__negative regulation of cholesterol biosynthetic process
                                                     |   |__negative regulation of cortisol biosynthetic process
                                                     |   |__negative regulation of ergosterol biosynthetic process
                                                     |   |__negative regulation of inositol biosynthetic process
                                                     |   |__negative regulation of inositol phosphate biosynthetic process(+)
                                                     |   |__negative regulation of kojic acid biosynthetic process
                                                     |   |__negative regulation of neosartoricin biosynthetic process
                                                     |   |__negative regulation of thiamine biosynthetic process
                                                     |__negative regulation of alcohol catabolic process
                                                     |__negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
                                                     |__negative regulation of androst-4-ene-3,17-dione biosynthetic process
                                                     |__negative regulation of arginine catabolic process
                                                     |__negative regulation of asperthecin biosynthetic process
                                                     |__negative regulation of bile acid biosynthetic process
                                                     |__negative regulation of cholesterol metabolic process
                                                     |   |__negative regulation of cholesterol biosynthetic process
                                                     |__negative regulation of citrulline biosynthetic process
                                                     |__negative regulation of ecdysteroid biosynthetic process
                                                     |__negative regulation of emericellamide biosynthetic process
                                                     |   |__negative regulation of emericellamide A biosynthetic process
                                                     |__negative regulation of emodin biosynthetic process
                                                     |__negative regulation of endocrocin biosynthetic process
                                                     |__negative regulation of fatty acid metabolic process 2 rec.
                                                     |   |__negative regulation of butyryl-CoA catabolic process to butanol
                                                     |   |__negative regulation of fatty acid biosynthetic process(+) 2 rec.
                                                     |   |__negative regulation of fatty acid oxidation(+)
                                                     |   |__negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid
                                                     |   |__negative regulation of palmitic acid catabolic process
                                                     |__negative regulation of ferulate catabolic process
                                                     |__negative regulation of fumagillin biosynthetic process
                                                     |__negative regulation of fumonisin biosynthetic process
                                                     |__negative regulation of gamma-aminobutyric acid catabolic process
                                                     |__negative regulation of gerfelin biosynthetic process
                                                     |__negative regulation of gibberellin biosynthetic process
                                                     |__negative regulation of gluconeogenesis
                                                     |__negative regulation of glucose catabolic process to lactate via pyruvate
                                                     |__negative regulation of glutamate metabolic process
                                                     |   |__negative regulation of ammonia assimilation cycle
                                                     |   |__negative regulation of L-proline catabolic process to L-glutamate
                                                     |   |__negative regulation of tetrapyrrole biosynthetic process from glutamate
                                                     |__negative regulation of glycolytic fermentation to ethanol
                                                     |__negative regulation of glyoxylate cycle
                                                     |__negative regulation of helvolic acid biosynthetic process
                                                     |__negative regulation of histidine biosynthetic process
                                                     |__negative regulation of homoserine biosynthetic process
                                                     |__negative regulation of indoleacetic acid biosynthetic process via tryptophan
                                                     |__negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway
                                                     |__negative regulation of L-dopa biosynthetic process
                                                     |__negative regulation of L-glutamine biosynthetic process
                                                     |__negative regulation of L-leucine biosynthetic process
                                                     |__negative regulation of L-proline biosynthetic process
                                                     |__negative regulation of lysine biosynthetic process via aminoadipic acid
                                                     |   |__negative regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine
                                                     |__negative regulation of methane biosynthetic process from formic acid
                                                     |__negative regulation of monodictyphenone biosynthetic process
                                                     |__negative regulation of naphtho-gamma-pyrone biosynthetic process
                                                     |__negative regulation of nucleoside metabolic process
                                                     |__negative regulation of nucleotide metabolic process 1 rec.
                                                     |   |__negative regulation of nucleotide biosynthetic process(+)
                                                     |   |__negative regulation of nucleotide catabolic process(+) 1 rec.
                                                     |   |__negative regulation of purine nucleotide metabolic process(+) 1 rec.
                                                     |__negative regulation of o-orsellinic acid biosynthetic process
                                                     |__negative regulation of ornithine catabolic process
                                                     |__negative regulation of penicillin biosynthetic process
                                                     |__negative regulation of penicillin catabolic process
                                                     |__negative regulation of progesterone biosynthetic process
                                                     |   |__negative regulation of progesterone biosynthesis involved in luteolysis
                                                     |__negative regulation of pseurotin A biosynthetic process
                                                     |__negative regulation of purine nucleobase metabolic process
                                                     |__negative regulation of pyrimidine nucleobase metabolic process
                                                     |__negative regulation of pyruvate decarboxylation to acetyl-CoA
                                                     |__negative regulation of quinolinate biosynthetic process
                                                     |__negative regulation of sarcinapterin biosynthetic process
                                                     |__negative regulation of tatiopterin biosynthetic process
                                                     |__negative regulation of tensidol A biosynthetic process
                                                     |__negative regulation of tensidol B biosynthetic process
                                                     |__negative regulation of testosterone biosynthetic process
                                                     |__negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA
                                                     |__negative regulation of ubiquinone biosynthetic process
                                                     |__negative regulation of UDP-N-acetylglucosamine biosynthetic process 1 rec.
                                                     |__negative regulation of urea catabolic process
                                                     |__negative regulation of vitamin metabolic process
                                                     |   |__negative regulation of L-ascorbic acid biosynthetic process
                                                     |   |__negative regulation of retinoic acid biosynthetic process
                                                     |   |__negative regulation of thiamine biosynthetic process
                                                     |   |__negative regulation of thiamine diphosphate biosynthetic process
                                                     |   |__negative regulation of vitamin D biosynthetic process
                                                     |__negative regulation of xanthone-containing compound biosynthetic process
                                                     |   |__negative regulation of emericellin biosynthetic process
                                                     |__negative regulation of xylose catabolic process to ethanol
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regulation of small molecule metabolic process
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