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| Term | ATG2-ATG18 complex | ID (Ontology) | GO:0062079 (Gene Ontology) |
| Definition | A protein complex essential for autophagy during nutrient deprivation, a catabolic process that sequesters undesired cellular material into autophagosomes for delivery to lysosomes for degradation. Contributes to nutrition homeostasis and damage control in eukaryotic cells. Functions at a late step of autophagosome formation for efficient completion of sequestration, probably through facilitating recruitment of ATG8-phosphatidylethanolamine (PE) to the preautophagosomal structure (PAS) and/or its protection from deconjugation by ATG4. Composed of ATG2 and ATG18 in Saccharomyces cerevisiae.[ PubMed:23230146 ] | ||
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phagophore assembly site |__phagophore assembly site membrane__ membrane | |__phagophore assembly site membrane__| |__membrane protein complex___________| protein-containing complex | |__membrane protein complex___________| ATG2-ATG18 complex |
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| Is a | membrane protein complex | ||
| Part of | phagophore assembly site membrane | ||
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